Nuclear receptor regulation of cholesterol and bile acid metabolism

Research output: Contribution to journalReview articlepeer-review

158 Scopus citations

Abstract

The metabolism of cholesterol and bile acids is transcriptionally regulated by classic feedforward and feedback signaling pathways. The mechanisms underlying this regulation have recently been elucidated by the characterization of three classes of orphan nuclear receptors. Furthermore, the study of these receptors suggests their potential as targets for new drug therapies.

Original languageEnglish (US)
Pages (from-to)557-563
Number of pages7
JournalCurrent Opinion in Biotechnology
Volume10
Issue number6
DOIs
StatePublished - Dec 1 1999

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biomedical Engineering

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