Nucleotide Excision Repair: Biology

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Nucleotide excision repair (NER) is a fundamental DNA repair process that is ubiquitously distributed from bacteria to humans. The process is essential for the enzyme-catalyzed removal of various types of base damage from the nuclear genome, typically those that result in significant distortion of the helical structure of DNA. This article discusses the overview and biology of NER.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Biological Chemistry
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages337-340
Number of pages4
ISBN (Electronic)9780123786319
ISBN (Print)9780123786302
DOIs
StatePublished - Feb 15 2013

Keywords

  • Human disease
  • Nucleotide excision repair
  • Pyrimidine dimmers
  • UV radiation
  • Xeroderma pigmentosum

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Friedberg, E. C. (2013). Nucleotide Excision Repair: Biology. In Encyclopedia of Biological Chemistry: Second Edition (pp. 337-340). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-378630-2.00254-1