Numb and Numblike control cell number during vertebrate neurogenesis

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A fundamental problem in nervous system development is how to control progenitor-cell divisions to generate the correct number of cells for the mature brain and spinal cord. A recent report by Petersen and colleagues has identified an essential role for Numb and a related protein, Numblike, in this process. This study demonstrates that Numb and Numblike function to maintain the self-renewal properties of neural progenitor cells in the vertebrate neural tube.

Original languageEnglish (US)
Pages (from-to)395-396
Number of pages2
JournalTrends in Neurosciences
Volume26
Issue number8
DOIs
StatePublished - Aug 1 2003

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Neurogenesis
Vertebrates
Stem Cells
Cell Count
Neural Tube
Cell Division
Nervous System
Spinal Cord
Brain
Proteins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Numb and Numblike control cell number during vertebrate neurogenesis. / Johnson, Jane E.

In: Trends in Neurosciences, Vol. 26, No. 8, 01.08.2003, p. 395-396.

Research output: Contribution to journalArticle

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