Nutrient and chemical sensing by intestinal pathogens

Juan D. Hernandez-Doria, Vanessa Sperandio

Research output: Contribution to journalShort survey

10 Scopus citations

Abstract

Pathogenic gut bacteria, such as those comprising the Enterobacteriaceae family, have evolved sophisticated virulence mechanisms, including nutrient and chemical sensing, to escape host defense strategies and produce disease. In this review we describe the mechanisms utilized by the enteric pathogen enterohemorrhagic Escherichia coli (EHEC) O157:H7 to achieve successful colonization of its mammalian host.

Original languageEnglish (US)
Pages (from-to)759-764
Number of pages6
JournalMicrobes and Infection
Volume15
Issue number12
DOIs
StatePublished - Nov 1 2013

Keywords

  • Enterobacteriaceae
  • Signals
  • Two-component system
  • Type-III secretion

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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