TY - JOUR
T1 - Obstructive sleep apnea in children with autism
AU - Tomkies, Anna
AU - Johnson, Romaine F.
AU - Shah, Gopi
AU - Caraballo, Michelle
AU - Evans, Patricia
AU - Mitchell, Ron B.
N1 - Publisher Copyright:
© 2019 American Academy of Sleep Medicine. All rights reserved.
PY - 2019/10/15
Y1 - 2019/10/15
N2 - Study Objectives: To describe the demographic and clinical characteristics of children with autism spectrum disorder (ASD) referred for polysomnography (PSG) and to look for predictors of obstructive sleep apnea (OSA) and severe OSA in these children. Methods: This is a retrospective case series of children ages 2 to 18 years who underwent PSG between January 2009 and February 2015. Children were excluded if they had major comorbidities, prior tonsillectomy, or missing data. The following information was collected: age, sex, race, height, weight, tonsil size, and prior diagnosis of allergies, asthma, gastroesophageal reflux disease, seizure disorder, developmental delay, cerebral palsy, or attention deficit hyperactivity disorder. Predictors of OSA were evaluated. Results: A total of 45 children were included with a mean (standard deviation [SD]) age of 6.1 years (2.8). The patients were 80% male, 49% Hispanic, 27% African American, 22% Caucasian, and 2.2% other. Of these children 26 (58%) had OSA (apnea-hypopnea index [AHI] > 1 event/h) and 15 (33%) were obese (body mass index, body mass index z-score ≥ 95th percentile). The mean (SD) AHI was 7.7 (15.0) events/h (range 1.0–76.6). A total of 9 (20%) had severe OSA (AHI ≥ 10 events/h). There were no demographic or clinical predictors of OSA in this group. However, increasing weight served as a predictor of severe OSA and African American or Hispanic children were more likely obese. Conclusions: The absence of demographic or clinical predictors of OSA supports using general indications for PSG in children with ASD.
AB - Study Objectives: To describe the demographic and clinical characteristics of children with autism spectrum disorder (ASD) referred for polysomnography (PSG) and to look for predictors of obstructive sleep apnea (OSA) and severe OSA in these children. Methods: This is a retrospective case series of children ages 2 to 18 years who underwent PSG between January 2009 and February 2015. Children were excluded if they had major comorbidities, prior tonsillectomy, or missing data. The following information was collected: age, sex, race, height, weight, tonsil size, and prior diagnosis of allergies, asthma, gastroesophageal reflux disease, seizure disorder, developmental delay, cerebral palsy, or attention deficit hyperactivity disorder. Predictors of OSA were evaluated. Results: A total of 45 children were included with a mean (standard deviation [SD]) age of 6.1 years (2.8). The patients were 80% male, 49% Hispanic, 27% African American, 22% Caucasian, and 2.2% other. Of these children 26 (58%) had OSA (apnea-hypopnea index [AHI] > 1 event/h) and 15 (33%) were obese (body mass index, body mass index z-score ≥ 95th percentile). The mean (SD) AHI was 7.7 (15.0) events/h (range 1.0–76.6). A total of 9 (20%) had severe OSA (AHI ≥ 10 events/h). There were no demographic or clinical predictors of OSA in this group. However, increasing weight served as a predictor of severe OSA and African American or Hispanic children were more likely obese. Conclusions: The absence of demographic or clinical predictors of OSA supports using general indications for PSG in children with ASD.
KW - Autism spectrum disorder
KW - Obstructive sleep apnea
KW - Polysomnography
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U2 - 10.5664/jcsm.7978
DO - 10.5664/jcsm.7978
M3 - Article
C2 - 31596212
AN - SCOPUS:85073062821
SN - 1550-9389
VL - 15
SP - 1469
EP - 1476
JO - Journal of Clinical Sleep Medicine
JF - Journal of Clinical Sleep Medicine
IS - 10
ER -