Seventy-four infants and children (ages 1 month to 16 years) were treated with either 30 mg/kg of cefadroxil once a day or 15 mg/kg of cefaclor twice a day for 10 days. The patients were followed up with urine cultures at 2-5, 12-15 and 24-30 days after completion of therapy. Thirty-six received cefadroxil and 38 cefaclor and each group were well matched with regard to age, sex and temperature. Eighty-nine per cent of infection pathogens were Escherichia coli. The rates of recurrence after treatment were similar for each treatment group (cefadroxil 13.9%, cefaclor 10.5%). The once daily dosing of cefadroxil was considered an advantage in assuring patient compliance.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of Antimicrobial Chemotherapy|
|Issue number||Suppl. B|
|Publication status||Published - 1982|
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