One pot synthesis and antibacterial activity of 3,5-dibromo-2,4-dihydroxy substituted chalcones

Anju Devpura, Parul Sharma, Sumer Singh Chundawat, Sheetal Shaktawat, Shiv S. Dulawat

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

In an effort to develop antibacterial agents, a series of chalcones were prepared by Claisen-Schmidt condensation of appropriate acetophenones with appropriate aromatic aldehydes in the presence of basic alumina as solid support reagent under microwave irradiation. The synthesized compounds were characterized by their IR, 1H NMR, mass spectral data and elemental analysis. The compounds have been screened for their antibacterial activity against S. aureus, S. fecalis, E. coli and P. mirbilis.

Original languageEnglish (US)
Pages (from-to)4649-4651
Number of pages3
JournalAsian Journal of Chemistry
Volume23
Issue number10
StatePublished - 2011
Externally publishedYes

Keywords

  • Antibacterial activity
  • Chalcone
  • Microwave
  • Solid-phase synthesis

ASJC Scopus subject areas

  • General Chemistry

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