One-pot synthesis of pyridazino[1,4]oxazin-3-ones

Chen Ma, Su Dong Cho, J. R. Falck, Dong Soo Shin

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Pyridazino[1,4]oxazin-3-ones were conveniently prepared in a one-pot condensation of N-substituted 2-chloroacetamides with various 5-chloro-pyridazin-6-ones via rearrangement of a spiro-aminoketal intermediate.

Original languageEnglish (US)
Pages (from-to)1399-1405
Number of pages7
JournalSynthetic Communications
Issue number8
StatePublished - 2004


  • Multi-drug resistant
  • One-pot synthesis
  • Pyridazino[1,4]oxazin-3-ones
  • X-ray analysis

ASJC Scopus subject areas

  • Organic Chemistry

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