Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element

Medicine & Life Sciences

• Sterol Regulatory Element Binding Proteins 100%
• 3-hydroxy-3-methylglutaryl-coenzyme A 86%
• Sterols 77%
• Oxidoreductases 60%
• Base Pairing 56%
• Mutation 37%
• Protein Binding 21%
• Plasmids 17%
• Chloramphenicol O-Acetyltransferase 14%
• Thymidine Kinase 13%
• 5' Flanking Region 13%
• LDL Receptors 12%
• DNA 12%
• Simplexvirus 12%
• Nuclear Proteins 11%
• Cricetinae 11%
• Mutagenesis 10%
• Genes 8%
• Binding Sites 8%
• Fibroblasts 8%
• Cholesterol 8%
• Phenotype 6%
• Enzymes 6%
• Proteins 4%

Chemical Compounds

• Coenzyme A 81%
• Sterol 72%
• Mutation 55%
• Protein 27%
• Chloramphenicol 26%
• Thymidine 24%
• Cholesterol 19%
• Biosynthesis 18%
• Binding Site 15%
• Substitution Reaction 13%
• Length 13%