Optical fiber readout of scintillator arrays using a multi-channel PMT: A high resolution PET detector for animal imaging

Simon R. Cherry; Yiping Shao; Stefan Siegel; Robert W. Silverman; Erkan Mumcuoglu; Ken Meadors; Michael E. Phelps

doi:10.1109/23.507249

Optical fiber readout of scintillator arrays using a multi-channel PMT: A high resolution PET detector for animal imaging

Simon R. Cherry, Yiping Shao, Stefan Siegel, Robert W. Silverman, Erkan Mumcuoglu, Ken Meadors, Michael E. Phelps

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

We report the results from a new high resolution gamma ray imaging detector designed for use in a positron emission tomography (PET) system dedicated to small animal imaging. The detectors consist of an 8 × 8 array of 2 × 2 × 10 mm bismuth germanate (BGO) crystals coupled by 2 mm diameter double clad optical fibers to a 64 pixel multi-channel photomultiplier tube (MC-PMT). A charge division readout board is used to convert the 64 output channels into four position sensitive signals which determine the crystal of interaction. Measurements with a pair of these detectors demonstrate an intrinsic spatial resolution of 1.4 mm, a coincidence timing resolution of 15 ns and an energy resolution ranging between 35 and 60%. Based on these encouraging results, the design for a dedicated animal PET tomograph is proposed and simulations of this system project a reconstructed resolution of less than 2 mm within a 5 cm diameter transaxial field of view.

Original language	English (US)
Pages (from-to)	1932-1937
Number of pages	6
Journal	IEEE Transactions on Nuclear Science
Volume	43
Issue number	3 PART 2
DOIs	https://doi.org/10.1109/23.507249
State	Published - 1996

ASJC Scopus subject areas

Nuclear and High Energy Physics
Nuclear Energy and Engineering
Electrical and Electronic Engineering

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10.1109/23.507249

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title = "Optical fiber readout of scintillator arrays using a multi-channel PMT: A high resolution PET detector for animal imaging",

abstract = "We report the results from a new high resolution gamma ray imaging detector designed for use in a positron emission tomography (PET) system dedicated to small animal imaging. The detectors consist of an 8 × 8 array of 2 × 2 × 10 mm bismuth germanate (BGO) crystals coupled by 2 mm diameter double clad optical fibers to a 64 pixel multi-channel photomultiplier tube (MC-PMT). A charge division readout board is used to convert the 64 output channels into four position sensitive signals which determine the crystal of interaction. Measurements with a pair of these detectors demonstrate an intrinsic spatial resolution of 1.4 mm, a coincidence timing resolution of 15 ns and an energy resolution ranging between 35 and 60%. Based on these encouraging results, the design for a dedicated animal PET tomograph is proposed and simulations of this system project a reconstructed resolution of less than 2 mm within a 5 cm diameter transaxial field of view.",

author = "Cherry, {Simon R.} and Yiping Shao and Stefan Siegel and Silverman, {Robert W.} and Erkan Mumcuoglu and Ken Meadors and Phelps, {Michael E.}",

note = "Funding Information: We would like to thank Wayne Seemungal of Philips Components for loaning us the two XP1722 MC-PMTs used in this study. We would further like to thank Esso Flykt (Philips), Stan Majewski (CEBAF), Mark Andreaco and Chuck Williams (CTI PET Systems Inc.) for their insight and useful suggestions. Finally, we offer our thanks to the staff of the UCLA PET Center and Cyclotron for providing the isotopes used in this study. This work was supported by a grant from The Whitaker Foundation.",

year = "1996",

doi = "10.1109/23.507249",

language = "English (US)",

volume = "43",

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publisher = "Institute of Electrical and Electronics Engineers Inc.",

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T2 - A high resolution PET detector for animal imaging

AU - Cherry, Simon R.

AU - Shao, Yiping

AU - Siegel, Stefan

AU - Silverman, Robert W.

AU - Mumcuoglu, Erkan

AU - Meadors, Ken

AU - Phelps, Michael E.

N1 - Funding Information: We would like to thank Wayne Seemungal of Philips Components for loaning us the two XP1722 MC-PMTs used in this study. We would further like to thank Esso Flykt (Philips), Stan Majewski (CEBAF), Mark Andreaco and Chuck Williams (CTI PET Systems Inc.) for their insight and useful suggestions. Finally, we offer our thanks to the staff of the UCLA PET Center and Cyclotron for providing the isotopes used in this study. This work was supported by a grant from The Whitaker Foundation.

PY - 1996

Y1 - 1996

N2 - We report the results from a new high resolution gamma ray imaging detector designed for use in a positron emission tomography (PET) system dedicated to small animal imaging. The detectors consist of an 8 × 8 array of 2 × 2 × 10 mm bismuth germanate (BGO) crystals coupled by 2 mm diameter double clad optical fibers to a 64 pixel multi-channel photomultiplier tube (MC-PMT). A charge division readout board is used to convert the 64 output channels into four position sensitive signals which determine the crystal of interaction. Measurements with a pair of these detectors demonstrate an intrinsic spatial resolution of 1.4 mm, a coincidence timing resolution of 15 ns and an energy resolution ranging between 35 and 60%. Based on these encouraging results, the design for a dedicated animal PET tomograph is proposed and simulations of this system project a reconstructed resolution of less than 2 mm within a 5 cm diameter transaxial field of view.

AB - We report the results from a new high resolution gamma ray imaging detector designed for use in a positron emission tomography (PET) system dedicated to small animal imaging. The detectors consist of an 8 × 8 array of 2 × 2 × 10 mm bismuth germanate (BGO) crystals coupled by 2 mm diameter double clad optical fibers to a 64 pixel multi-channel photomultiplier tube (MC-PMT). A charge division readout board is used to convert the 64 output channels into four position sensitive signals which determine the crystal of interaction. Measurements with a pair of these detectors demonstrate an intrinsic spatial resolution of 1.4 mm, a coincidence timing resolution of 15 ns and an energy resolution ranging between 35 and 60%. Based on these encouraging results, the design for a dedicated animal PET tomograph is proposed and simulations of this system project a reconstructed resolution of less than 2 mm within a 5 cm diameter transaxial field of view.

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Optical fiber readout of scintillator arrays using a multi-channel PMT: A high resolution PET detector for animal imaging

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