Optical reflectance spectroscopy for detection of human prostate cancer

Vikrant Sharma, Dheerendra Kashyap, Aditya Mathker, Sweta Narvenkar, Karim Bensalah, Wareef Kabbani, Altug Tuncel, Jeffrey A Cadeddu, Hanli Liu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Scopus citations

Abstract

We present the method and application of optical reflectance spectroscopy to differentiate prostate cancer from normal tissue using a needle like, bifurcated, fiber-optic probe. An analytical expression to model light reflectance recently published by Zonios et. al. was used to derive optical properties of tissue. A total of 23 cases of human prostate specimens were investigated to analyze statistical differences between the respective cancerous tissues versus normal tissues. The results demonstrate that the derived hemodynamic parameters and optical properties can serve as good bio-markers to differentiate tumor tissue from normal tissue in human prostate.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publicationEngineering the Future of Biomedicine, EMBC 2009
PublisherIEEE Computer Society
Pages118-121
Number of pages4
ISBN (Print)9781424432967
DOIs
StatePublished - Jan 1 2009
Event31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States
Duration: Sep 2 2009Sep 6 2009

Publication series

NameProceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009

Other

Other31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
CountryUnited States
CityMinneapolis, MN
Period9/2/099/6/09

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Biomedical Engineering
  • Medicine(all)

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  • Cite this

    Sharma, V., Kashyap, D., Mathker, A., Narvenkar, S., Bensalah, K., Kabbani, W., Tuncel, A., Cadeddu, J. A., & Liu, H. (2009). Optical reflectance spectroscopy for detection of human prostate cancer. In Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 (pp. 118-121). [5334830] (Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009). IEEE Computer Society. https://doi.org/10.1109/IEMBS.2009.5334830