Optimization of blood-myocardial contrast in 3D true FISP cardiac imaging at 1.5 T

Petros Martirosian, Gerald F. Greil, Michael Fenchel, Ulrich Kramer, Stefan Miller, Andreas Greiser, Claus D. Claussen, Fritz Schick, Ludger Sieverding

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Three-dimensional (3D) steady-state free precession (SSFP) MRI sequences are often applied to visualize both intra- and extracardiac pathologies. In the present study the contrast behavior of 3D true fast imaging with steady precession (True-FISP) sequences for cardiac imaging was optimized in numerical simulations and compared with measurements obtained in eight healthy volunteers on a 1.5 T whole-body scanner. Two SS preparation schemes in combination with and without a T2 preparation were assessed to improve contrast between blood and myocardium using a navigator-gated and ECG-triggered 3D True-FISP sequence. Numerical simulations and experimental studies in volunteers showed that an SS preparation using a constant flip angle (CFA) is preferable to a linear flip angle (LFA) preparation in terms of contrast between blood and myocardium. The optimized 3D True-FISP sequence provides a reliable, accurate, and time-efficient means of obtaining a morphological cardiac diagnosis.

Original languageEnglish (US)
Pages (from-to)213-219
Number of pages7
JournalMagnetic resonance in medicine
Issue number1
StatePublished - Jan 2007


  • Blood-myocardial contrast
  • Steady-state preparation
  • T preparation
  • True-FISP
  • Whole-heart MRI

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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