Optimizing Therapeutic Effects in Patients with Comorbidities: Drug-Resistant Tremor, Autonomic Dysfunction, Psychiatric Disorders, and Cognitive Impairment

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3 Citations (Scopus)

Abstract

Parkinsonism is a syndrome characterized by a combination of cardinal features including resting tremor, bradykinesia, rigidity, and loss of postural reflexes. The most common presentation of parkinsonism is the idiopathic variety first described by James Parkinson in 1817 now known as Parkinson's disease (PD). This article focuses on identifying the different subtypes of PD, with the recognition that treatment approaches may differ depending on the initial presenting feature. It also addresses issues related to the recognition and treatment of nonmotor comorbidities of PD, such as autonomic dysfunction and neuropsychiatric problems including depression and dementia.

Original languageEnglish (US)
Pages (from-to)29-44
Number of pages16
JournalNeurologic Clinics
Volume26
Issue number3 SUPPL.
DOIs
StatePublished - Aug 2008

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Tremor
Therapeutic Uses
Parkinson Disease
Psychiatry
Comorbidity
Parkinsonian Disorders
Pharmaceutical Preparations
Hypokinesia
Reflex
Dementia
Depression
Therapeutics
Cognitive Dysfunction

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

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title = "Optimizing Therapeutic Effects in Patients with Comorbidities: Drug-Resistant Tremor, Autonomic Dysfunction, Psychiatric Disorders, and Cognitive Impairment",
abstract = "Parkinsonism is a syndrome characterized by a combination of cardinal features including resting tremor, bradykinesia, rigidity, and loss of postural reflexes. The most common presentation of parkinsonism is the idiopathic variety first described by James Parkinson in 1817 now known as Parkinson's disease (PD). This article focuses on identifying the different subtypes of PD, with the recognition that treatment approaches may differ depending on the initial presenting feature. It also addresses issues related to the recognition and treatment of nonmotor comorbidities of PD, such as autonomic dysfunction and neuropsychiatric problems including depression and dementia.",
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