Oral analgesia compared with intravenous patient-controlled analgesia for pain after cesarean delivery: A randomized controlled trial

Kathryn M. Davis, Matthew A. Esposito, Bruce A. Meyer

Research output: Contribution to journalArticle

41 Scopus citations


Objective: The purpose of this study was to determine whether oral analgesia with oxycodone-acetaminophen or a patient-controlled analgesia device with morphine provides superior analgesia after cesarean delivery. Study design: Ninety-three patients with scheduled cesarean delivery were assigned randomly to receive either oral analgesia with oxycodone-acetaminophen or a morphine patient-controlled analgesia device. At 6 and 24 hours after the procedure, pain was assessed on a visual analog pain scale of 0 to 10. Nausea, sedation, pruritus, ambulation, emesis, and oral fluid intake were also assessed. Results: Patients who used oral analgesia without a patient-controlled analgesia device experienced less pain at 6 and 24 hours after cesarean delivery. They also had less nausea and drowsiness at 6 hours but slightly more nausea at 24 hours. Conclusion: Oral analgesia with oxycodone-acetaminophen may offer superior pain control after cesarean delivery with fewer side-effects as compared with morphine patient-controlled analgesia. Consideration should be given to expanding the use of oral analgesia in patients immediately after cesarean delivery.

Original languageEnglish (US)
Pages (from-to)967-971
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Issue number4
Publication statusPublished - Apr 2006



  • Cesarean delivery
  • Oral analgesia
  • Postoperative pain

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

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