Orexin Neurons and the TASK of Glucosensing

Michael M. Scott, Jacob N. Marcus, Joel K. Elmquist

Research output: Contribution to journalShort survey

2 Scopus citations

Abstract

Relatively little is known about the mechanisms that link changing levels of glucose and neuronal activity. A paper in the current issue of Neuron by Burdakov et al. demonstrates that orexin/hypocretin neurons are inhibited by rising glucose in part due to membrane potential effects mediated by tandem-pore K+ (K2P) channels. The findings may shed light on the mechanisms that link hypoglycemia and coordinated arousal and autonomic responses.

Original languageEnglish (US)
Pages (from-to)665-667
Number of pages3
JournalNeuron
Volume50
Issue number5
DOIs
StatePublished - Jun 1 2006

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Orexin Neurons and the TASK of Glucosensing'. Together they form a unique fingerprint.

  • Cite this