Orexin Neurons and the TASK of Glucosensing

Michael M. Scott, Jacob N. Marcus, Joel K. Elmquist

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Relatively little is known about the mechanisms that link changing levels of glucose and neuronal activity. A paper in the current issue of Neuron by Burdakov et al. demonstrates that orexin/hypocretin neurons are inhibited by rising glucose in part due to membrane potential effects mediated by tandem-pore K+ (K2P) channels. The findings may shed light on the mechanisms that link hypoglycemia and coordinated arousal and autonomic responses.

Original languageEnglish (US)
Pages (from-to)665-667
Number of pages3
JournalNeuron
Volume50
Issue number5
DOIs
StatePublished - Jun 1 2006

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Neurons
Glucose
Arousal
Hypoglycemia
Membrane Potentials
Orexins

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Orexin Neurons and the TASK of Glucosensing. / Scott, Michael M.; Marcus, Jacob N.; Elmquist, Joel K.

In: Neuron, Vol. 50, No. 5, 01.06.2006, p. 665-667.

Research output: Contribution to journalArticle

Scott, Michael M. ; Marcus, Jacob N. ; Elmquist, Joel K. / Orexin Neurons and the TASK of Glucosensing. In: Neuron. 2006 ; Vol. 50, No. 5. pp. 665-667.
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