Abstract
Organocuprates efficiently undergo reaction with heterocyclic propargyl mesylates at low temperature to produce N-fused heterocycles. The copper reagent plays a "double duty" in this cascade transformation, which proceeds through an S N2'-substitution followed by a consequent cycloisomerization step.
Original language | English (US) |
---|---|
Pages (from-to) | 1816-1827 |
Number of pages | 12 |
Journal | Khimiya Geterotsiklicheskikh Soedinenii |
Issue number | 12 |
State | Published - Dec 1 2011 |
Externally published | Yes |
Keywords
- Allenes
- Cycloisomerization
- Indolizines
- Propargyl mesylates
- Synthetic methods
ASJC Scopus subject areas
- Organic Chemistry