O⁶-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3- bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogeneous MGMT⁺/MGMT^- xenografts after BCNU and O⁶-benzylguanine plus BCNU

Weldon P. Phillips, James K V Willson, Sanford D. Markowitz, Elizabeth Zborowska, Nasir H. Zaidi, Lili Liu, Nahida H. Gordon, Stanton L. Gerson

Simmons Comprehensive Cancer Center

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

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O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3- bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogeneous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU

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Medicine & Life Sciences

O⁶-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3- bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogeneous MGMT⁺/MGMT^- xenografts after BCNU and O⁶-benzylguanine plus BCNU