Other primary malignancies in patients with uterine corpus malignancy

Jacquelyn B. Delin, David Scott Miller, Robert L. Coleman

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Objective: The purpose of this study was to determine the occurrence of multiple primary malignancies in patients with uterine corpus malignancy. Study design: We conducted a tumor registry search and a medical record review. Results: Uterine corpus malignancy was reported in 1505 of 25,605 women (6%) in the registries, of which 131 of 1505 women (9%) had multiple primary malignancies. Patients with uterine corpus malignancy with multiple primary malignancies were more likely to have had pri-mary malignancies of the ovary (relative risk, 10; 95% CI, 6.2-17) and colon (relative risk, 2; 95% CI, 1.0-4.3) and less likely to have had primary malignancies of the cervix (relative risk, 0.4; 95% CI, 0.17-0.97) compared with women who had only one primary malignancy. A family history of malignancy was reported in only 44% of the patients with uterine corpus malignancy with multiple primary malignancies and 32% of those patients whose multiple primary malignancies were from the ovary or colon. Conclusion: The development of multiple primary malignancies in patients with uterine corpus malignancy may indicate an inherited predisposition, especially in those patients whose multiple primary malignancies include the ovary or colon. That predisposition may not be detected by routine family history.

Original languageEnglish (US)
Pages (from-to)1429-1431
Number of pages3
JournalAmerican Journal of Obstetrics and Gynecology
Volume190
Issue number5
DOIs
StatePublished - May 2004

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Neoplasms
Ovary
Colon
Registries
Cervix Uteri
Medical Records

Keywords

  • Neoplasm

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

Other primary malignancies in patients with uterine corpus malignancy. / Delin, Jacquelyn B.; Miller, David Scott; Coleman, Robert L.

In: American Journal of Obstetrics and Gynecology, Vol. 190, No. 5, 05.2004, p. 1429-1431.

Research output: Contribution to journalArticle

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