Outcome of congenital diaphragmatic hernia repair depending on patch type

C. A. Laituri, C. L. Garey, P. A. Valusek, F. B. Fike, A. J. Kaye, D. J. Ostlie, C. L. Snyder, S. D. St. Peter

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Introduction: Patch repair of a congenital diaphragmatic hernia is associated with a much higher rate of recurrence than when primary repair is feasible. The biosynthetic options for the repair materials continue to expand. We therefore reviewed our experience to benchmark complication rates as we progress with the use of new materials. Methods: A retrospective review was conducted of all patients who underwent repair of congenital diaphragmatic hernia from January 1994 to May 2009. Results: Of the 155 patients included in the study, 101 patients had primary closure and 54 received a diaphragmatic patch. The rates of recurrence, Small Bowel Obstruction (SBO), and subsequent abdominal operation were all significantly higher in the group of patients requiring patch repair. There were 3 types of patch repairs: 37 patients received a SIS patch, 12 had a nonabsorbable patch, and 5 received an AlloDerm patch. The incidence of SBO in patients with a nonabsorbable mesh was 17% and was associated with a 50% recurrence rate and 67% re-recurrence rate. SIS was associated with 19% incidence of SBO, a recurrence rate of 22% and a 50% re-recurrence rate, whereas AlloDerm had a 40% incidence of SBO, 40% recurrence rate, and 100% re-recurrence rate. Discussion: As we move towards the next generation of materials, these data do not justify the continued comparison with nonabsorbable patches. We do not have enough comparative data to define a superior biosynthetic material, but we plan to use our data on SIS to benchmark our experience with future generation materials.

Original languageEnglish (US)
Pages (from-to)363-365
Number of pages3
JournalEuropean Journal of Pediatric Surgery
Volume20
Issue number6
DOIs
StatePublished - Dec 23 2010

Fingerprint

Herniorrhaphy
Recurrence
Benchmarking
Incidence
Congenital Diaphragmatic Hernias
Social Responsibility

Keywords

  • congenital diaphragmatic hernia
  • obstruction
  • patch
  • recurrence

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

Cite this

Laituri, C. A., Garey, C. L., Valusek, P. A., Fike, F. B., Kaye, A. J., Ostlie, D. J., ... St. Peter, S. D. (2010). Outcome of congenital diaphragmatic hernia repair depending on patch type. European Journal of Pediatric Surgery, 20(6), 363-365. https://doi.org/10.1055/s-0030-1261939

Outcome of congenital diaphragmatic hernia repair depending on patch type. / Laituri, C. A.; Garey, C. L.; Valusek, P. A.; Fike, F. B.; Kaye, A. J.; Ostlie, D. J.; Snyder, C. L.; St. Peter, S. D.

In: European Journal of Pediatric Surgery, Vol. 20, No. 6, 23.12.2010, p. 363-365.

Research output: Contribution to journalArticle

Laituri, CA, Garey, CL, Valusek, PA, Fike, FB, Kaye, AJ, Ostlie, DJ, Snyder, CL & St. Peter, SD 2010, 'Outcome of congenital diaphragmatic hernia repair depending on patch type', European Journal of Pediatric Surgery, vol. 20, no. 6, pp. 363-365. https://doi.org/10.1055/s-0030-1261939
Laituri CA, Garey CL, Valusek PA, Fike FB, Kaye AJ, Ostlie DJ et al. Outcome of congenital diaphragmatic hernia repair depending on patch type. European Journal of Pediatric Surgery. 2010 Dec 23;20(6):363-365. https://doi.org/10.1055/s-0030-1261939
Laituri, C. A. ; Garey, C. L. ; Valusek, P. A. ; Fike, F. B. ; Kaye, A. J. ; Ostlie, D. J. ; Snyder, C. L. ; St. Peter, S. D. / Outcome of congenital diaphragmatic hernia repair depending on patch type. In: European Journal of Pediatric Surgery. 2010 ; Vol. 20, No. 6. pp. 363-365.
@article{3927b9e7801f4bc59c4a33ab5011a3d9,
title = "Outcome of congenital diaphragmatic hernia repair depending on patch type",
abstract = "Introduction: Patch repair of a congenital diaphragmatic hernia is associated with a much higher rate of recurrence than when primary repair is feasible. The biosynthetic options for the repair materials continue to expand. We therefore reviewed our experience to benchmark complication rates as we progress with the use of new materials. Methods: A retrospective review was conducted of all patients who underwent repair of congenital diaphragmatic hernia from January 1994 to May 2009. Results: Of the 155 patients included in the study, 101 patients had primary closure and 54 received a diaphragmatic patch. The rates of recurrence, Small Bowel Obstruction (SBO), and subsequent abdominal operation were all significantly higher in the group of patients requiring patch repair. There were 3 types of patch repairs: 37 patients received a SIS patch, 12 had a nonabsorbable patch, and 5 received an AlloDerm patch. The incidence of SBO in patients with a nonabsorbable mesh was 17{\%} and was associated with a 50{\%} recurrence rate and 67{\%} re-recurrence rate. SIS was associated with 19{\%} incidence of SBO, a recurrence rate of 22{\%} and a 50{\%} re-recurrence rate, whereas AlloDerm had a 40{\%} incidence of SBO, 40{\%} recurrence rate, and 100{\%} re-recurrence rate. Discussion: As we move towards the next generation of materials, these data do not justify the continued comparison with nonabsorbable patches. We do not have enough comparative data to define a superior biosynthetic material, but we plan to use our data on SIS to benchmark our experience with future generation materials.",
keywords = "congenital diaphragmatic hernia, obstruction, patch, recurrence",
author = "Laituri, {C. A.} and Garey, {C. L.} and Valusek, {P. A.} and Fike, {F. B.} and Kaye, {A. J.} and Ostlie, {D. J.} and Snyder, {C. L.} and {St. Peter}, {S. D.}",
year = "2010",
month = "12",
day = "23",
doi = "10.1055/s-0030-1261939",
language = "English (US)",
volume = "20",
pages = "363--365",
journal = "European Journal of Pediatric Surgery",
issn = "0939-7248",
publisher = "Thieme Medical Publishers",
number = "6",

}

TY - JOUR

T1 - Outcome of congenital diaphragmatic hernia repair depending on patch type

AU - Laituri, C. A.

AU - Garey, C. L.

AU - Valusek, P. A.

AU - Fike, F. B.

AU - Kaye, A. J.

AU - Ostlie, D. J.

AU - Snyder, C. L.

AU - St. Peter, S. D.

PY - 2010/12/23

Y1 - 2010/12/23

N2 - Introduction: Patch repair of a congenital diaphragmatic hernia is associated with a much higher rate of recurrence than when primary repair is feasible. The biosynthetic options for the repair materials continue to expand. We therefore reviewed our experience to benchmark complication rates as we progress with the use of new materials. Methods: A retrospective review was conducted of all patients who underwent repair of congenital diaphragmatic hernia from January 1994 to May 2009. Results: Of the 155 patients included in the study, 101 patients had primary closure and 54 received a diaphragmatic patch. The rates of recurrence, Small Bowel Obstruction (SBO), and subsequent abdominal operation were all significantly higher in the group of patients requiring patch repair. There were 3 types of patch repairs: 37 patients received a SIS patch, 12 had a nonabsorbable patch, and 5 received an AlloDerm patch. The incidence of SBO in patients with a nonabsorbable mesh was 17% and was associated with a 50% recurrence rate and 67% re-recurrence rate. SIS was associated with 19% incidence of SBO, a recurrence rate of 22% and a 50% re-recurrence rate, whereas AlloDerm had a 40% incidence of SBO, 40% recurrence rate, and 100% re-recurrence rate. Discussion: As we move towards the next generation of materials, these data do not justify the continued comparison with nonabsorbable patches. We do not have enough comparative data to define a superior biosynthetic material, but we plan to use our data on SIS to benchmark our experience with future generation materials.

AB - Introduction: Patch repair of a congenital diaphragmatic hernia is associated with a much higher rate of recurrence than when primary repair is feasible. The biosynthetic options for the repair materials continue to expand. We therefore reviewed our experience to benchmark complication rates as we progress with the use of new materials. Methods: A retrospective review was conducted of all patients who underwent repair of congenital diaphragmatic hernia from January 1994 to May 2009. Results: Of the 155 patients included in the study, 101 patients had primary closure and 54 received a diaphragmatic patch. The rates of recurrence, Small Bowel Obstruction (SBO), and subsequent abdominal operation were all significantly higher in the group of patients requiring patch repair. There were 3 types of patch repairs: 37 patients received a SIS patch, 12 had a nonabsorbable patch, and 5 received an AlloDerm patch. The incidence of SBO in patients with a nonabsorbable mesh was 17% and was associated with a 50% recurrence rate and 67% re-recurrence rate. SIS was associated with 19% incidence of SBO, a recurrence rate of 22% and a 50% re-recurrence rate, whereas AlloDerm had a 40% incidence of SBO, 40% recurrence rate, and 100% re-recurrence rate. Discussion: As we move towards the next generation of materials, these data do not justify the continued comparison with nonabsorbable patches. We do not have enough comparative data to define a superior biosynthetic material, but we plan to use our data on SIS to benchmark our experience with future generation materials.

KW - congenital diaphragmatic hernia

KW - obstruction

KW - patch

KW - recurrence

UR - http://www.scopus.com/inward/record.url?scp=78650268279&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650268279&partnerID=8YFLogxK

U2 - 10.1055/s-0030-1261939

DO - 10.1055/s-0030-1261939

M3 - Article

C2 - 20954106

AN - SCOPUS:78650268279

VL - 20

SP - 363

EP - 365

JO - European Journal of Pediatric Surgery

JF - European Journal of Pediatric Surgery

SN - 0939-7248

IS - 6

ER -