Outcome of Transcatheter Aortic Valve Implantation in Patients with Peripheral Vascular Disease

F. Darmoch, M. Chadi Alraies, Yasser Al-khadra, Homam Moussa Pacha, Mohamad Soud, Amir Kaki, Tanveer Rab, Cindy L. Grines, Rodrigo Bagur, Chun Shing Kwok, M. Mamas, Subhash Banerjee, Wael AlJaroudi, Duane S. Pinto

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Peripheral vascular disease (PVD) is common in patients referred for transcatheter aortic valve implantation (TAVI). We sought to investigate the impact of PVD on patients who underwent TAVI. Using data from the National Inpatient Sample database 2011 and 2014, we identified patients who had undergone TAVI. We studied the clinical characteristics and procedural outcomes in patients with PVD who underwent TAVI compared with those patients without PVD using propensity score matching score matching. Results: A total of 42,215 patients underwent TAVI; of which 1,388 patients were matched using propensity score matched scores to 694 in each (PVD vs no PVD) patients. The population had a mean age of 81 years old and 55.8% were of female gender. African-Americans constituted 4.3%. PVD patients who underwent TAVI were found to have higher rates of vascular complications (11.8% vs 5.9 % p <0.001) compared with non-PVD patients and tended to have higher mortality (5.5% vs 3.6%, p = 0.121) and post-TAVI bleeding (13.5% vs 12% p = 0.143). In conclusion, PVD patients have higher in-hospital mortality and higher incidence of in-hospital overall complications compared with patients who have no PVD.

Original languageEnglish (US)
Pages (from-to)416-422
Number of pages7
JournalAmerican Journal of Cardiology
Volume124
Issue number3
DOIs
StatePublished - Aug 1 2019

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Darmoch, F., Alraies, M. C., Al-khadra, Y., Pacha, H. M., Soud, M., Kaki, A., Rab, T., Grines, C. L., Bagur, R., Kwok, C. S., Mamas, M., Banerjee, S., AlJaroudi, W., & Pinto, D. S. (2019). Outcome of Transcatheter Aortic Valve Implantation in Patients with Peripheral Vascular Disease. American Journal of Cardiology, 124(3), 416-422. https://doi.org/10.1016/j.amjcard.2019.04.047