TY - JOUR
T1 - Outcomes of Extracorporeal Membrane Oxygenation Support for Complex High-Risk Elective Percutaneous Coronary Interventions
T2 - A Single-Center Experience and Review of the Literature
AU - Shaukat, Arslan
AU - Hryniewicz-Czeneszew, Katarzyna
AU - Sun, Benjamin
AU - Mudy, Karol
AU - Wilson, Kelly
AU - Tajti, Peter
AU - Stanberry, Larissa
AU - Garberich, Ross
AU - Sandoval, Yader
AU - Burke, M. Nicholas
AU - Chavez, Ivan
AU - Gössl, Mario
AU - Henry, Timothy
AU - Lips, Daniel
AU - Mooney, Michael
AU - Poulose, Anil
AU - Sorajja, Paul
AU - Traverse, Jay
AU - Wang, Yale
AU - Bradley, Steven
AU - Brilakis, Emmanouil S
N1 - Funding Information:
This research was supported by the Minneapolis Heart Institute Foundation. However, no funds were used in conducting the study.
Publisher Copyright:
© 2018 HMP Communications.
PY - 2018/12
Y1 - 2018/12
N2 - OBJECTIVES: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is most commonly used in patients with cardiac arrest and cardiogenic shock. There are limited data on the use of VA-ECMO for elective, high-risk percutaneous coronary intervention (PCI). We examined the in-hospital and mid-term clinical outcomes in patients undergoing complex, high-risk PCI with VA-ECMO support. METHODS:. We conducted a retrospective review of ECMO-supported elective high-risk PCIs performed at our institution between May 2012 and May 2017. The electronic medical records and angiograms were individually reviewed. We assessed the in-hospital and mid-term major adverse cardiovascular and cerebrovascular event (MACCE) rates, and reviewed bleeding and vascular complications. RESULTS: Five patients underwent elective high-risk PCI with ECMO support. Mean age was 66.8 ± 8.6 years and all patients were men. The mean ejection fraction was 26.6 ± 18.0%. Most procedures were unprotected left main PCIs. All PCIs were successful; 1 patient required femoral artery surgical repair. The mean hospital stay post procedure was 6.4 ± 2.0 days. ECMO was successfully weaned in all cases, and the duration of ECMO was <24 hours in 4 cases. There was no occurrence of in-hospital and 1-year MACCE. CONCLUSION: ECMO can be successfully used for hemodynamic support during elective high-risk PCI.
AB - OBJECTIVES: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is most commonly used in patients with cardiac arrest and cardiogenic shock. There are limited data on the use of VA-ECMO for elective, high-risk percutaneous coronary intervention (PCI). We examined the in-hospital and mid-term clinical outcomes in patients undergoing complex, high-risk PCI with VA-ECMO support. METHODS:. We conducted a retrospective review of ECMO-supported elective high-risk PCIs performed at our institution between May 2012 and May 2017. The electronic medical records and angiograms were individually reviewed. We assessed the in-hospital and mid-term major adverse cardiovascular and cerebrovascular event (MACCE) rates, and reviewed bleeding and vascular complications. RESULTS: Five patients underwent elective high-risk PCI with ECMO support. Mean age was 66.8 ± 8.6 years and all patients were men. The mean ejection fraction was 26.6 ± 18.0%. Most procedures were unprotected left main PCIs. All PCIs were successful; 1 patient required femoral artery surgical repair. The mean hospital stay post procedure was 6.4 ± 2.0 days. ECMO was successfully weaned in all cases, and the duration of ECMO was <24 hours in 4 cases. There was no occurrence of in-hospital and 1-year MACCE. CONCLUSION: ECMO can be successfully used for hemodynamic support during elective high-risk PCI.
KW - Extracorporeal membrane oxygenation
KW - High-risk PCI
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M3 - Article
C2 - 30504514
AN - SCOPUS:85057746398
SN - 1042-3931
VL - 30
SP - 456
EP - 460
JO - Journal of Invasive Cardiology
JF - Journal of Invasive Cardiology
IS - 12
ER -