Outcomes of extremely preterm infants after delivery room cardiopulmonary resuscitation in a population-based cohort

S. C. Handley, Y. Sun, M. H. Wyckoff, H. C. Lee

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Objective:To describe the relationship of delivery room cardiopulmonary resuscitation (DR-CPR) to short-term outcomes of extremely preterm infants.Study design:This was a cohort study of 22 to 27+6/7 weeks gestational age (GA) infants during 2005 to 2011. DR-CPR was defined as chest compressions and/or epinephrine administration. Multivariable logistic regression was used to estimate odds ratios (ORs) with 95% confidence intervals (CIs) associated with DR-CPR; analysis was stratified by GA.Result:Of the 13 758 infants, 856 (6.2%) received DR-CPR. Infants 22 to 23+6/7 weeks receiving DR-CPR had similar outcomes to non-recipients. Infants 24 to 25+6/7 weeks receiving DR-CPR had more severe intraventricular hemorrhage (OR 1.36, 95% CI 1.07, 1.72). Infants 26 to 27+6/7 weeks receiving DR-CPR were more likely to die (OR 1.81, 95% CI 1.30, 2.51) and have intraventricular hemorrhage (OR 2.10, 95% CI 1.56, 2.82). Adjusted hospital DR-CPR rates varied widely (median 5.7%).Conclusion:Premature infants receiving DR-CPR had worse outcomes. Mortality and morbidity varied by GA.

Original languageEnglish (US)
Pages (from-to)379-383
Number of pages5
JournalJournal of Perinatology
Volume35
Issue number5
DOIs
StatePublished - May 30 2015

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Extremely Premature Infants
Delivery Rooms
Cardiopulmonary Resuscitation
Population
Odds Ratio
Confidence Intervals
Gestational Age
Hemorrhage
Premature Infants
Epinephrine
Cohort Studies
Thorax
Logistic Models
Morbidity

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Pediatrics, Perinatology, and Child Health

Cite this

Outcomes of extremely preterm infants after delivery room cardiopulmonary resuscitation in a population-based cohort. / Handley, S. C.; Sun, Y.; Wyckoff, M. H.; Lee, H. C.

In: Journal of Perinatology, Vol. 35, No. 5, 30.05.2015, p. 379-383.

Research output: Contribution to journalArticle

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