Outreach invitations for FIT and colonoscopy improve colorectal cancer screening rates: A randomized controlled trial in a safety-net health system

Amit G. Singal, Samir Gupta, Jasmin A. Tiro, Celette Sugg Skinner, Katharine Mccallister, Joanne M. Sanders, Wendy Pechero Bishop, Deepak Agrawal, Christian A. Mayorga, Chul Ahn, Adam C. Loewen, Noel O. Santini, Ethan A. Halm

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

BACKGROUND: The effectiveness of colorectal cancer (CRC) screening is limited by underuse, particularly among underserved populations. Among a racially diverse and socioeconomically disadvantaged cohort of patients, the authors compared the effectiveness of fecal immunochemical test (FIT) outreach and colonoscopy outreach to increase screening participation rates, compared with usual visit-based care. METHODS: Patients aged 50 to 64 years who were not up-to-date with CRC screening but used primary care services in a large safety-net health system were randomly assigned to mailed FIT outreach (2400 patients), mailed colonoscopy outreach (2400 patients), or usual care with opportunistic visit-based screening (1199 patients). Patients who did not respond to outreach invitations within 2 weeks received follow-up telephone reminders. The primary outcome was CRC screening completion within 12 months after randomization. RESULTS: Baseline patient characteristics across the 3 groups were similar. Using intention-to-screen analysis, screening participation rates were higher for FIT outreach (58.8%) and colonoscopy outreach (42.4%) than usual care (29.6%) (P

Original languageEnglish (US)
JournalCancer
DOIs
StateAccepted/In press - 2015

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Colonoscopy
Early Detection of Cancer
Colorectal Neoplasms
Randomized Controlled Trials
Safety
Health
Vulnerable Populations
Random Allocation
Telephone
Primary Health Care

Keywords

  • Colonoscopy
  • Colorectal cancer screening
  • Fecal immunochemical test
  • Navigation
  • Randomized controlled trial
  • Safety-net health system

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Outreach invitations for FIT and colonoscopy improve colorectal cancer screening rates : A randomized controlled trial in a safety-net health system. / Singal, Amit G.; Gupta, Samir; Tiro, Jasmin A.; Skinner, Celette Sugg; Mccallister, Katharine; Sanders, Joanne M.; Bishop, Wendy Pechero; Agrawal, Deepak; Mayorga, Christian A.; Ahn, Chul; Loewen, Adam C.; Santini, Noel O.; Halm, Ethan A.

In: Cancer, 2015.

Research output: Contribution to journalArticle

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abstract = "BACKGROUND: The effectiveness of colorectal cancer (CRC) screening is limited by underuse, particularly among underserved populations. Among a racially diverse and socioeconomically disadvantaged cohort of patients, the authors compared the effectiveness of fecal immunochemical test (FIT) outreach and colonoscopy outreach to increase screening participation rates, compared with usual visit-based care. METHODS: Patients aged 50 to 64 years who were not up-to-date with CRC screening but used primary care services in a large safety-net health system were randomly assigned to mailed FIT outreach (2400 patients), mailed colonoscopy outreach (2400 patients), or usual care with opportunistic visit-based screening (1199 patients). Patients who did not respond to outreach invitations within 2 weeks received follow-up telephone reminders. The primary outcome was CRC screening completion within 12 months after randomization. RESULTS: Baseline patient characteristics across the 3 groups were similar. Using intention-to-screen analysis, screening participation rates were higher for FIT outreach (58.8{\%}) and colonoscopy outreach (42.4{\%}) than usual care (29.6{\%}) (P",
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AU - Singal, Amit G.

AU - Gupta, Samir

AU - Tiro, Jasmin A.

AU - Skinner, Celette Sugg

AU - Mccallister, Katharine

AU - Sanders, Joanne M.

AU - Bishop, Wendy Pechero

AU - Agrawal, Deepak

AU - Mayorga, Christian A.

AU - Ahn, Chul

AU - Loewen, Adam C.

AU - Santini, Noel O.

AU - Halm, Ethan A.

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