TY - JOUR
T1 - Oxygenttm
T2 - A novel probe of tissue oxygen tension
AU - Mason, R. P.
AU - Shukla, H.
AU - Antich, P. P.
PY - 1992/1
Y1 - 1992/1
N2 - We have examined the 19F NMR spectrum and relaxation behavior of Oxygent (an emulsion of perfluorooctylbromide). Each of the resonances exhibits a linear relationship between spin-lattice relaxation rate and oxygen tension at constant temperature. Oxygent provides enhanced sensitivity to changes in oxygen tension compared with other emulsions used previously. We have used Oxygentto determine the oxygen tension in the liver of a mouse. References 1 Thomas, S. R. (1985), in “NMR in Medicine: The instrumentation and clinical applications”, (Thomas, S.R. & Dixon, R. L. eds.) Medical Physics monograph #14 pp269-289.
AB - We have examined the 19F NMR spectrum and relaxation behavior of Oxygent (an emulsion of perfluorooctylbromide). Each of the resonances exhibits a linear relationship between spin-lattice relaxation rate and oxygen tension at constant temperature. Oxygent provides enhanced sensitivity to changes in oxygen tension compared with other emulsions used previously. We have used Oxygentto determine the oxygen tension in the liver of a mouse. References 1 Thomas, S. R. (1985), in “NMR in Medicine: The instrumentation and clinical applications”, (Thomas, S.R. & Dixon, R. L. eds.) Medical Physics monograph #14 pp269-289.
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U2 - 10.3109/10731199209119744
DO - 10.3109/10731199209119744
M3 - Article
C2 - 1391536
AN - SCOPUS:0026611658
SN - 1055-7172
VL - 20
SP - 929
EP - 932
JO - Biomaterials, Artificial Cells and Immobilization Biotechnology
JF - Biomaterials, Artificial Cells and Immobilization Biotechnology
IS - 4 --Feb
ER -