Oxygent(TM)

A novel probe of tissue oxygen tension

R. P. Mason, H. Shukla, P. P. Antich

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We have examined the 19F NMR spectrum and relaxation behavior of Oxygent(TM) (an emulsion of perfluorooctylbromide). Each of the resonances exhibits a linear relationship between spin-lattice relaxation rate and oxygen tension at constant temperature. Oxygent(TM) provides enhanced sensitivity to changes in oxygen tension compared with other emulsions used previously. We have used Oxygent(TM) to determine the oxygen tension in the liver of a mouse.

Original languageEnglish (US)
Pages (from-to)929-932
Number of pages4
JournalBiomaterials, Artificial Cells, and Immobilization Biotechnology
Volume20
Issue number2-4
StatePublished - 1992

Fingerprint

Tissue
Oxygen
Emulsions
Spin-lattice relaxation
Liver
Nuclear magnetic resonance
Temperature
perflubron

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Oxygent(TM) : A novel probe of tissue oxygen tension. / Mason, R. P.; Shukla, H.; Antich, P. P.

In: Biomaterials, Artificial Cells, and Immobilization Biotechnology, Vol. 20, No. 2-4, 1992, p. 929-932.

Research output: Contribution to journalArticle

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