Oxygenttm: A novel probe of tissue oxygen tension

R. P. Mason, H. Shukla, P. P. Antich

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

We have examined the 19F NMR spectrum and relaxation behavior of Oxygent (an emulsion of perfluorooctylbromide). Each of the resonances exhibits a linear relationship between spin-lattice relaxation rate and oxygen tension at constant temperature. Oxygent provides enhanced sensitivity to changes in oxygen tension compared with other emulsions used previously. We have used Oxygentto determine the oxygen tension in the liver of a mouse. References 1 Thomas, S. R. (1985), in “NMR in Medicine: The instrumentation and clinical applications”, (Thomas, S.R. & Dixon, R. L. eds.) Medical Physics monograph #14 pp269-289.

Original languageEnglish (US)
Pages (from-to)929-932
Number of pages4
JournalBiomaterials, Artificial Cells and Immobilization Biotechnology
Volume20
Issue number4 --Feb
DOIs
StatePublished - Jan 1992

    Fingerprint

ASJC Scopus subject areas

  • Medicine(all)

Cite this