Paediatric systemic lupus erythematosus: insights from translational research

Tracey B. Wright; Marilynn Punaro

doi:10.1093/rheumatology/kew447

Paediatric systemic lupus erythematosus: insights from translational research

Tracey B. Wright, Marilynn Punaro

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focused clinical monitoring and assessment of response to treatment. This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research.

Original language	English (US)
Pages (from-to)	i24-i31
Journal	Rheumatology (Oxford, England)
Volume	56
Issue number	1
DOIs	https://doi.org/10.1093/rheumatology/kew447
State	Published - Apr 1 2017

Keywords

biomarker
microarray
paediatric
systemic lupus erythematosus

ASJC Scopus subject areas

Rheumatology
Pharmacology (medical)

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10.1093/rheumatology/kew447

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title = "Paediatric systemic lupus erythematosus: insights from translational research",

abstract = "Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focused clinical monitoring and assessment of response to treatment. This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research.",

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author = "Wright, {Tracey B.} and Marilynn Punaro",

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T2 - insights from translational research

AU - Wright, Tracey B.

AU - Punaro, Marilynn

N1 - Publisher Copyright: © The Author 2017. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

PY - 2017/4/1

Y1 - 2017/4/1

N2 - Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focused clinical monitoring and assessment of response to treatment. This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research.

AB - Investigations in paediatric SLE contributed significantly to the discovery of the association of type I IFNs with lupus and underscored the potential application of this knowledge by informing the use of glucocorticoid therapy. Recent, promising research reveals biomarkers that may yield more focused clinical monitoring and assessment of response to treatment. This article reviews unique features of paediatric SLE and details important developments in paediatric lupus research.

KW - biomarker

KW - microarray

KW - paediatric

KW - systemic lupus erythematosus

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M3 - Review article

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AN - SCOPUS:85021855587

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JO - Rheumatology (Oxford, England)

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ER -

Paediatric systemic lupus erythematosus: insights from translational research

Abstract

Keywords

ASJC Scopus subject areas

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