Palladium catalyzed cross-coupling and tandem cyclization-coupling of α-halo(thio)ethers with organotins

R. K. Bhatt, Shin Dong-Soo, J. R. Falck, Charles Mioskowski

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Pd(0) mediates the cross-coupling of organotins with a variety of α-haloethers/thioethers in moderate-good yields whereas an α-chloroacetoxyalkene failed to react. Tandem cyclization-coupling of the alkyl-palladium intermediate affords novel access to heterocycles.

Original languageEnglish (US)
Pages (from-to)4885-4888
Number of pages4
JournalTetrahedron Letters
Volume33
Issue number34
DOIs
StatePublished - Aug 18 1992

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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