Palladium-catalyzed direct functionalization of imidazolinone

Synthesis of dibromophakellstatin

Jianming Lu, Xianghui Tan, Chuo Chen

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

The direct C-H functionalization of imidazolinone is achieved with Pd(OAc)2/NaOAc in DMSO. Dibromophakellstatin can be synthesized in five steps with 40% overall yield using this new C-H activation method.

Original languageEnglish (US)
Pages (from-to)7768-7769
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number25
DOIs
StatePublished - Jun 27 2007

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Palladium
Dimethyl Sulfoxide
Chemical activation
palladium(II) acetate
dibromophakellstatin

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Palladium-catalyzed direct functionalization of imidazolinone : Synthesis of dibromophakellstatin. / Lu, Jianming; Tan, Xianghui; Chen, Chuo.

In: Journal of the American Chemical Society, Vol. 129, No. 25, 27.06.2007, p. 7768-7769.

Research output: Contribution to journalArticle

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