Palladium-catalyzed direct functionalization of imidazolinone: Synthesis of dibromophakellstatin

Jianming Lu, Xianghui Tan, Chuo Chen

Research output: Contribution to journalArticle

72 Scopus citations


The direct C-H functionalization of imidazolinone is achieved with Pd(OAc)2/NaOAc in DMSO. Dibromophakellstatin can be synthesized in five steps with 40% overall yield using this new C-H activation method.

Original languageEnglish (US)
Pages (from-to)7768-7769
Number of pages2
JournalJournal of the American Chemical Society
Issue number25
Publication statusPublished - Jun 27 2007


ASJC Scopus subject areas

  • Chemistry(all)

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