Palliation of hepatic tumors

Steven C. Cunningham, Michael A. Choti, Emily C. Bellavance, Timothy M. Pawlik

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

Palliation is treatment aimed at alleviating the symptomatic effects of a disease rather than at curing the disease. The four most common types of liver tumors that often require palliative treatment include hepatocellular carcinoma (HCC), cholangiocarcinoma (CC), metastatic colorectal carcinoma (mCRC), and metastatic neuroendocrine tumors (mNET). Modalities employed in the palliative treatment of these tumors most often include resection, stenting, chemotherapy, radiation, ablation, and the general treatment of liver failure symptoms. Many of these modalities can be applied to the palliative care of all hepatic tumor types, regardless of the specific tumor histology-as incurable cancers often converge along a final common pathway. We herein provide a review of the therapeutic approaches to palliate hepatic tumors, as well as how such therapies are designed to alleviate the symptoms of patients with end-stage liver tumors.

Original languageEnglish (US)
Pages (from-to)277-291
Number of pages15
JournalSurgical Oncology
Volume16
Issue number4
DOIs
Publication statusPublished - Dec 2007

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Keywords

  • Hepatic tumors
  • Interventions
  • Palliation
  • Symptom relief

ASJC Scopus subject areas

  • Oncology
  • Surgery

Cite this

Cunningham, S. C., Choti, M. A., Bellavance, E. C., & Pawlik, T. M. (2007). Palliation of hepatic tumors. Surgical Oncology, 16(4), 277-291. https://doi.org/10.1016/j.suronc.2007.08.010