PARADOXICAL EXPANSION OF INTRACRANIAL TUBERCULOMAS DURING CHEMOTHERAPY

S. T. Chambers, C. Record, W. A. Hendrickse, Peter Rudge, Hillas Smith

Research output: Contribution to journalArticlepeer-review

82 Scopus citations

Abstract

4 patients with tuberculosis, 3 of whom had tuberculous meningitis, were noted to have tuberculomas on computed tomographic scanning. During antituberculous chemotherapy the intracranial lesions increased in size in all 4 patients at a time when the clinical state and cerebrospinal-fluid abnormalities were improving; in 2 of the patients the regional lymph nodes also enlarged greatly. Though the expansion of the cerebral lesions caused anxiety and led to some changes in chemotherapy, the lesions eventually diminished in size.

Original languageEnglish (US)
Pages (from-to)181-184
Number of pages4
JournalThe Lancet
Volume324
Issue number8396
DOIs
StatePublished - Jul 28 1984

ASJC Scopus subject areas

  • Medicine(all)

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