Paraneoplastic neuromuscular disorders

Lydia Sharp, Steven Vernino

Research output: Contribution to journalReview article

21 Scopus citations

Abstract

Introduction: Paraneoplastic neurological disorders are rare autoimmune conditions that can affect any part of the nervous system, including the peripheral nervous system. These disorders are associated with certain types of cancer, and the peripheral nervous system dysfunction often precedes the symptoms from the cancer itself. Methods: This investigation was undertaken as a topic review. Conclusions: Learning to recognize paraneoplastic neuromuscular disorders, the associated antibodies and their implications, and the appropriate screening modalities can, in some cases, lead to an earlier diagnosis of cancer. Eliminating the cancer, if present, and immunomodulation can potentially improve the symptoms and clinical outcome.

Original languageEnglish (US)
Pages (from-to)839-840
Number of pages2
JournalMuscle and Nerve
Volume46
Issue number6
DOIs
StatePublished - Dec 2012

    Fingerprint

Keywords

  • Antibodies
  • Cancer
  • Myasthenia
  • Myositis
  • Neuropathy

ASJC Scopus subject areas

  • Physiology
  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)

Cite this