Paraneoplastic neuromuscular disorders

Lydia Sharp, Steven Vernino

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Introduction: Paraneoplastic neurological disorders are rare autoimmune conditions that can affect any part of the nervous system, including the peripheral nervous system. These disorders are associated with certain types of cancer, and the peripheral nervous system dysfunction often precedes the symptoms from the cancer itself. Methods: This investigation was undertaken as a topic review. Conclusions: Learning to recognize paraneoplastic neuromuscular disorders, the associated antibodies and their implications, and the appropriate screening modalities can, in some cases, lead to an earlier diagnosis of cancer. Eliminating the cancer, if present, and immunomodulation can potentially improve the symptoms and clinical outcome.

Original languageEnglish (US)
Pages (from-to)841-850
Number of pages10
JournalMuscle and Nerve
Volume46
Issue number6
DOIs
StatePublished - Dec 2012

Fingerprint

Peripheral Nervous System
Neoplasms
Immunomodulation
Nervous System Diseases
Early Detection of Cancer
Nervous System
Learning
Antibodies

Keywords

  • Antibodies
  • Cancer
  • Myasthenia
  • Myositis
  • Neuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Cellular and Molecular Neuroscience
  • Physiology (medical)
  • Physiology

Cite this

Paraneoplastic neuromuscular disorders. / Sharp, Lydia; Vernino, Steven.

In: Muscle and Nerve, Vol. 46, No. 6, 12.2012, p. 841-850.

Research output: Contribution to journalArticle

Sharp, Lydia ; Vernino, Steven. / Paraneoplastic neuromuscular disorders. In: Muscle and Nerve. 2012 ; Vol. 46, No. 6. pp. 841-850.
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