PARP around the Clock

Vivek Kumar, Joseph S. Takahashi

Research output: Contribution to journalShort survey

7 Scopus citations

Abstract

Cells possess internal ~24 hr or circadian clocks that synchronize physiological processes with daily cycles of light and nutrient availability. In this issue, Asher et al. (2010) find that PARP-1 (poly(ADP-ribose) polymerase 1) modifies components of the clock machinery in response to feeding, providing a mechanism for how metabolic rhythms coordinate with circadian rhythms.

Original languageEnglish (US)
Pages (from-to)841-843
Number of pages3
JournalCell
Volume142
Issue number6
DOIs
StatePublished - Sep 1 2010

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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