PARPs and ADP-ribosylation: 60 years on

Research output: Contribution to journalReview article

Abstract

Work on PARPs-a family of enzymes that catalyze ADP-ribosylation, a posttranslational modification of proteins-has resulted in major advances and reached important milestones. The past decade has seen new discoveries in areas well beyond the historical focus on DNA repair, which are having impacts on the understanding and treatment of human disease. This special focus section of Genes & Development includes seven reviews that highlight these discoveries and point theway forward for future advances in the field.

Original languageEnglish (US)
Pages (from-to)251-253
Number of pages3
JournalGenes and Development
Volume34
Issue number5
DOIs
StatePublished - Mar 1 2020

Keywords

  • ADP-ribosylation
  • PARPs
  • Posttranslational modification

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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