Partial Fanconi syndrome induced by ifosfamide

Muhammad Ajmal Panezai; Charles Owen; Harold M. Szerlip

doi:10.1080/08998280.2018.1536020

Partial Fanconi syndrome induced by ifosfamide

Muhammad Ajmal Panezai, Charles Owen, Harold M. Szerlip

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Ifosfamide-induced proximal tubular nephropathy can present as a spectrum of disease, from isolated hyperaminoaciduria to a partial or complete Fanconi syndrome. We report a case of ifosfamide-induced partial Fanconi syndrome in a man with metastatic progressive Ewing sarcoma and put forth a hypothesis on the mechanism.

Original language	English (US)
Pages (from-to)	73-74
Number of pages	2
Journal	Baylor University Medical Center Proceedings
Volume	32
Issue number	1
DOIs	https://doi.org/10.1080/08998280.2018.1536020
State	Published - Jan 2 2019
Externally published	Yes

Keywords

Acrolein
Ewing sarcoma
Fanconi syndrome
Na-K-ATPase
chloroacetaldehyde
hyperaminoaciduria
ifosfamide
nephrotoxicity
proximal tubulopathy

ASJC Scopus subject areas

General Medicine

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10.1080/08998280.2018.1536020

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abstract = "Ifosfamide-induced proximal tubular nephropathy can present as a spectrum of disease, from isolated hyperaminoaciduria to a partial or complete Fanconi syndrome. We report a case of ifosfamide-induced partial Fanconi syndrome in a man with metastatic progressive Ewing sarcoma and put forth a hypothesis on the mechanism.",

keywords = "Acrolein, Ewing sarcoma, Fanconi syndrome, Na-K-ATPase, chloroacetaldehyde, hyperaminoaciduria, ifosfamide, nephrotoxicity, proximal tubulopathy",

author = "Panezai, {Muhammad Ajmal} and Charles Owen and Szerlip, {Harold M.}",

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doi = "10.1080/08998280.2018.1536020",

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AU - Owen, Charles

AU - Szerlip, Harold M.

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AB - Ifosfamide-induced proximal tubular nephropathy can present as a spectrum of disease, from isolated hyperaminoaciduria to a partial or complete Fanconi syndrome. We report a case of ifosfamide-induced partial Fanconi syndrome in a man with metastatic progressive Ewing sarcoma and put forth a hypothesis on the mechanism.

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KW - Fanconi syndrome

KW - Na-K-ATPase

KW - chloroacetaldehyde

KW - hyperaminoaciduria

KW - ifosfamide

KW - nephrotoxicity

KW - proximal tubulopathy

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Partial Fanconi syndrome induced by ifosfamide

Abstract

Keywords

ASJC Scopus subject areas

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