Pathogenesis and cost-effectiveness of preventing kidney stones

Research output: Contribution to journalArticle

Abstract

Nephrolithiasis is a common problem that results in considerable cost and morbidity. Stone risk is associated with multiple risk factors such as diet and fluid intake, age, gender, ethnicity, geography, occupation, and comorbidities such as diabetes and obesity. There is evidence that high volume intake can reduce the risk of stone disease by 40% to 50%. While there are currently no recommendations to prevent kidney stones, a strategy to reduce risk of stone formation, such as increasing fluid intake, could reduce both morbidity and cost of stone disease. Using France as amodel, increased intake ofwater (>2L/d) results in considerable cost savings ranging from €273 million in a highly compliant population to €68 million in a population of low compliance (25%). Focusing prevention strategies on high-risk populations can significantly increase cost effectiveness. Future prospective studies will be necessary to demonstrate the potential benefits of primary prevention of nephrolithiasis.

Original languageEnglish (US)
JournalNutrition Today
Volume48
Issue number4
DOIs
StatePublished - Jul 2013

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Kidney Calculi
Cost-Benefit Analysis
Nephrolithiasis
Population
Morbidity
Geography
Cost of Illness
Cost Savings
Primary Prevention
Occupations
Compliance
France
Comorbidity
Obesity
Prospective Studies
Diet
Costs and Cost Analysis

ASJC Scopus subject areas

  • Nutrition and Dietetics

Cite this

Pathogenesis and cost-effectiveness of preventing kidney stones. / Lotan, Yair.

In: Nutrition Today, Vol. 48, No. 4, 07.2013.

Research output: Contribution to journalArticle

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