Pathogenesis of mucous membrane pemphigoid

A. Shadi Kourosh, Kim B. Yancey

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Mucous membrane pemphigoid (MMP) is the clinical phenotype of a group of autoimmune blistering diseases characterized by autoantibodies directed against different structural proteins in epidermal basement membranes. The clinical course and prognosis of MMP are affected by the specific autoantigen targeted, the titer and bioactivity profile of corresponding autoantibodies, and the specific mucosal sites of disease activity. Irreversible scarring and loss of function must be prevented by early diagnosis and appropriate interventions.

Original languageEnglish (US)
Pages (from-to)479-484
Number of pages6
JournalDermatologic Clinics
Volume29
Issue number3
DOIs
StatePublished - Jul 2011

Fingerprint

Bullous Pemphigoid
Autoantibodies
Mucous Membrane
Autoantigens
Basement Membrane
Autoimmune Diseases
Cicatrix
Early Diagnosis
Phenotype
Proteins

Keywords

  • Autoimmune
  • Mucous membrane
  • Pathogenesis
  • Pemphigoid

ASJC Scopus subject areas

  • Dermatology

Cite this

Pathogenesis of mucous membrane pemphigoid. / Kourosh, A. Shadi; Yancey, Kim B.

In: Dermatologic Clinics, Vol. 29, No. 3, 07.2011, p. 479-484.

Research output: Contribution to journalArticle

Kourosh, A. Shadi ; Yancey, Kim B. / Pathogenesis of mucous membrane pemphigoid. In: Dermatologic Clinics. 2011 ; Vol. 29, No. 3. pp. 479-484.
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