Renal cell carcinomas (RCC) are tumors that arise from the renal tubular epithelium. It encompasses a group of heterogeneous tumors with diverse clinical, pathological, and molecular characteristics as well as distinct prognosis and therapeutic responses. We review the pathological and molecular characteristics of major histological subtypes of RCC that are recognized by the 2004 World Health Organization (WHO) classification of renal tumors. We also discuss several newly described subtypes of RCC and RCC associated with inherited cancer syndromes. The prognostic significance of various histological parameters is also highlighted.
|Original language||English (US)|
|Title of host publication||Renal Cancer|
|Subtitle of host publication||Contemporary Management|
|Publisher||Springer New York|
|Number of pages||19|
|State||Published - Jan 1 2013|
ASJC Scopus subject areas