Patterns of failure in treatment of stage I and II diffuse malignant lymphoid tumors

L. E. Kun, J. D. Cox, R. Komaki

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Fifty-nine patients with Stage I and II diffuse malignant lymphoid tumors were irradiated between 1966 and 1979. Seventeen had primary lymph node disease and 42 had extranodal presentations and 8 of 36 extranodal distributions. Failures occurred in unirradiated lymph nodes (contiguous or transdiaphragmatic) in 3 of 17 patients with lymph node disease and 6 of 42 with extranodal disease. Dissemination occurred in 4 of 17 lymph node presentations and 6 of 42 extranodal tumors. Local recurrence was low, particularly among lymphatic tumors. There was no identifiable dose effect for local control. Extension to contiguous or distant lymph nodes occurred in 15% of cases. The authors suggest that the transdiaphragmatic lymph nodes be included when treating patients with lymph node tumors. The role of adjuvant chemotherapy remains unproved.

Original languageEnglish (US)
Pages (from-to)791-794
Number of pages4
JournalRADIOLOGY
Volume141
Issue number3
DOIs
StatePublished - Jan 1 1981

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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