Abstract
Dystonia is a disorder of involuntary sustained muscle contraction, which usually affects a focal region of the body but may be generalized and results in twisting contorted movements or abnormal postures. Several clinical subtypes of dystonia have been delineated and many have a strong inherited basis. In this issue of Neuron, de Carvalho Aguiar and colleagues report the identification of missense mutations in the gene for the Na+/K+-ATPase α3 subunit (ATP1A3) as a cause of rapid-onset dystonia-parkinsonism (RDP, DYT12).
Original language | English (US) |
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Pages (from-to) | 153-154 |
Number of pages | 2 |
Journal | Neuron |
Volume | 43 |
Issue number | 2 |
DOIs | |
State | Published - Jul 22 2004 |
ASJC Scopus subject areas
- General Neuroscience