Pd(N,N-dimethyl β-alaninate)2 as a high-turnover-number, phosphine-free catalyst for the suzuki reaction

Xin Cui; Tian Qin; Jia Rui Wang; Lei Liu; Qing Xiang Guo

doi:10.1055/s-2007-965883

Pd(N,N-dimethyl β-alaninate)₂ as a high-turnover-number, phosphine-free catalyst for the suzuki reaction

Xin Cui, Tian Qin, Jia Rui Wang, Lei Liu, Qing Xiang Guo

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

A novel crystalline, air- and moisture-stable Pd salt, Pd(N,N-dimethyl β-alaninate)₂, was synthesized. This salt was demonstrated to constitute a low-priced, phosphine-free, yet high-turnover-number (TON = 10 ⁴) catalyst for the Suzuki reactions of various aryl bromides and iodides under mild and simple reaction conditions. Moreover, it was observed that the presence of an olefin could dramatically hamper the Suzuki reaction.

Original language	English (US)
Pages (from-to)	393-399
Number of pages	7
Journal	Synthesis
Issue number	3
DOIs	https://doi.org/10.1055/s-2007-965883
State	Published - Feb 1 2007
Externally published	Yes

Keywords

High-turnover-number catalyst
Palladium
Phosphine-free ligand
Suzuki reaction

ASJC Scopus subject areas

Catalysis
Organic Chemistry

Access to Document

10.1055/s-2007-965883

Cite this

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title = "Pd(N,N-dimethyl β-alaninate)2 as a high-turnover-number, phosphine-free catalyst for the suzuki reaction",

abstract = "A novel crystalline, air- and moisture-stable Pd salt, Pd(N,N-dimethyl β-alaninate)2, was synthesized. This salt was demonstrated to constitute a low-priced, phosphine-free, yet high-turnover-number (TON = 10 4) catalyst for the Suzuki reactions of various aryl bromides and iodides under mild and simple reaction conditions. Moreover, it was observed that the presence of an olefin could dramatically hamper the Suzuki reaction.",

keywords = "High-turnover-number catalyst, Palladium, Phosphine-free ligand, Suzuki reaction",

author = "Xin Cui and Tian Qin and Wang, {Jia Rui} and Lei Liu and Guo, {Qing Xiang}",

year = "2007",

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doi = "10.1055/s-2007-965883",

language = "English (US)",

pages = "393--399",

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T1 - Pd(N,N-dimethyl β-alaninate)2 as a high-turnover-number, phosphine-free catalyst for the suzuki reaction

AU - Cui, Xin

AU - Qin, Tian

AU - Wang, Jia Rui

AU - Liu, Lei

AU - Guo, Qing Xiang

PY - 2007/2/1

Y1 - 2007/2/1

N2 - A novel crystalline, air- and moisture-stable Pd salt, Pd(N,N-dimethyl β-alaninate)2, was synthesized. This salt was demonstrated to constitute a low-priced, phosphine-free, yet high-turnover-number (TON = 10 4) catalyst for the Suzuki reactions of various aryl bromides and iodides under mild and simple reaction conditions. Moreover, it was observed that the presence of an olefin could dramatically hamper the Suzuki reaction.

AB - A novel crystalline, air- and moisture-stable Pd salt, Pd(N,N-dimethyl β-alaninate)2, was synthesized. This salt was demonstrated to constitute a low-priced, phosphine-free, yet high-turnover-number (TON = 10 4) catalyst for the Suzuki reactions of various aryl bromides and iodides under mild and simple reaction conditions. Moreover, it was observed that the presence of an olefin could dramatically hamper the Suzuki reaction.

KW - High-turnover-number catalyst

KW - Palladium

KW - Phosphine-free ligand

KW - Suzuki reaction

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DO - 10.1055/s-2007-965883

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EP - 399

JO - Synthesis

JF - Synthesis

IS - 3

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