PDZ domain proteins: Scaffolds for signaling complexes

Rama Ranganathan, Elliott M. Ross

Research output: Contribution to journalArticle

128 Citations (Scopus)

Abstract

InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.

Original languageEnglish (US)
JournalCurrent Biology
Volume7
Issue number12
StatePublished - Dec 1 1997

Fingerprint

scaffolding proteins
PDZ Domains
photoreceptors
Scaffolds
Drosophila
Conservation
Membrane Proteins
Proteins
proteins
Membranes

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

PDZ domain proteins : Scaffolds for signaling complexes. / Ranganathan, Rama; Ross, Elliott M.

In: Current Biology, Vol. 7, No. 12, 01.12.1997.

Research output: Contribution to journalArticle

@article{0c79d37844894254b30b9522f1573e0b,
title = "PDZ domain proteins: Scaffolds for signaling complexes",
abstract = "InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.",
author = "Rama Ranganathan and Ross, {Elliott M.}",
year = "1997",
month = "12",
day = "1",
language = "English (US)",
volume = "7",
journal = "Current Biology",
issn = "0960-9822",
publisher = "Cell Press",
number = "12",

}

TY - JOUR

T1 - PDZ domain proteins

T2 - Scaffolds for signaling complexes

AU - Ranganathan, Rama

AU - Ross, Elliott M.

PY - 1997/12/1

Y1 - 1997/12/1

N2 - InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.

AB - InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.

UR - http://www.scopus.com/inward/record.url?scp=0031460029&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031460029&partnerID=8YFLogxK

M3 - Article

C2 - 9382826

AN - SCOPUS:0031460029

VL - 7

JO - Current Biology

JF - Current Biology

SN - 0960-9822

IS - 12

ER -