PDZ domain proteins: Scaffolds for signaling complexes

Rama Ranganathan, Elliott M. Ross

Research output: Contribution to journalReview article

131 Scopus citations

Abstract

InaD, a Drosophila photoreceptor scaffolding protein, assembles multiple signal-transducing proteins at the membrane via its five PDZ domains, enhancing speed and efficiency of vision. Extensive conservation of PDZ domains suggests that these motifs have a general role in organizing diverse signaling complexes.

Original languageEnglish (US)
Pages (from-to)R770-R773
JournalCurrent Biology
Volume7
Issue number12
DOIs
StatePublished - Dec 1 1997

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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