Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management

Cynthia X. Wang, Benjamin M. Greenberg

Research output: Contribution to journalReview article

1 Scopus citations

Abstract

Pediatric-onset multiple sclerosis (MS) is a rare but increasingly recognized condition that both parallels and diverges from adult-onset MS. Exposure to key risk determinants for MS disease pathogenesis may occur during childhood. The diagnosis of pediatric MS can be challenging due to potential for atypical presentations and a broad differential diagnosis. MS disease-modifying therapies have not been rigorously studied in children and raise difficult questions on how to manage a chronic inflammatory neurologic disease in a population of patients with developing central nervous and immune systems.

Original languageEnglish (US)
Pages (from-to)135-149
Number of pages15
JournalNeurologic Clinics
Volume36
Issue number1
DOIs
StatePublished - Feb 1 2018

Keywords

  • Children
  • Demyelination
  • Diagnosis
  • Multiple sclerosis
  • Treatment

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management'. Together they form a unique fingerprint.

  • Cite this