Pediatric Multiple Sclerosis: From Recognition to Practical Clinical Management

Cynthia X. Wang, Benjamin M. Greenberg

Research output: Contribution to journalReview article

Abstract

Pediatric-onset multiple sclerosis (MS) is a rare but increasingly recognized condition that both parallels and diverges from adult-onset MS. Exposure to key risk determinants for MS disease pathogenesis may occur during childhood. The diagnosis of pediatric MS can be challenging due to potential for atypical presentations and a broad differential diagnosis. MS disease-modifying therapies have not been rigorously studied in children and raise difficult questions on how to manage a chronic inflammatory neurologic disease in a population of patients with developing central nervous and immune systems.

Original languageEnglish (US)
Pages (from-to)135-149
Number of pages15
JournalNeurologic Clinics
Volume36
Issue number1
DOIs
StatePublished - Feb 1 2018

Fingerprint

Multiple Sclerosis
Pediatrics
Nervous System Diseases
Immune System
Differential Diagnosis
Central Nervous System
Population
Therapeutics

Keywords

  • Children
  • Demyelination
  • Diagnosis
  • Multiple sclerosis
  • Treatment

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Pediatric Multiple Sclerosis : From Recognition to Practical Clinical Management. / Wang, Cynthia X.; Greenberg, Benjamin M.

In: Neurologic Clinics, Vol. 36, No. 1, 01.02.2018, p. 135-149.

Research output: Contribution to journalReview article

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