Pediatric obstructive sleep apnea and quality of life: A meta-analysis

Cristina M. Baldassari, Ronald B. Mitchell, Christine Schubert, Emily F. Rudnick

Research output: Contribution to journalArticle

108 Citations (Scopus)

Abstract

Objective: 1) To assess the quality of life (QOL) in children with obstructive sleep apnea (OSA) compared with QOL of children with chronic medical conditions, and 2) To determine QOL in children with OSA after adenotonsillectomy in short- and long-term follow-up. Data Sources/Review Methods: A literature review on QOL in pediatric OSA using the PubMed database. Results: The literature search yielded 10 articles that satisfied inclusion and exclusion criteria. In three studies, the Child Health Questionnaire (CHQ) survey was used to compare 193 patients who had OSA with 93 children who had juvenile rheumatoid arthritis (JRA) and with 815 healthy children. Of 12 CHQ subscale scores for children with OSA, 8 scores were significantly lower (indicating a poorer QOL) than controls. Children with OSA scored 19.23 points lower than healthy children in the subscale of parental impact-emotional. Children with OSA had QOL scores that were similar to those of children with JRA. In seven publications, 369 children with OSA undergoing adenotonsillectomy were studied by using the OSA-18 QOL instrument. The total OSA-18 score and each of the domain scores showed significant improvement (P < 0.0001) after adenotonsillectomy. At long-term follow-up, QOL scores remained significantly improved. Conclusions: Pediatric OSA has a significant impact on QOL. QOL in pediatric OSA is similar to that of children with JRA. Large improvements in QOL occur after adenotonsillectomy, and these findings are maintained in the long-term. The literature lacks control studies on QOL in pediatric OSA.

Original languageEnglish (US)
JournalOtolaryngology - Head and Neck Surgery
Volume138
Issue number3
DOIs
StatePublished - Mar 2008

Fingerprint

Obstructive Sleep Apnea
Meta-Analysis
Quality of Life
Pediatrics
Juvenile Arthritis
Information Storage and Retrieval
Health Surveys
PubMed
Quality Control
Publications
Databases

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Pediatric obstructive sleep apnea and quality of life : A meta-analysis. / Baldassari, Cristina M.; Mitchell, Ronald B.; Schubert, Christine; Rudnick, Emily F.

In: Otolaryngology - Head and Neck Surgery, Vol. 138, No. 3, 03.2008.

Research output: Contribution to journalArticle

Baldassari, Cristina M. ; Mitchell, Ronald B. ; Schubert, Christine ; Rudnick, Emily F. / Pediatric obstructive sleep apnea and quality of life : A meta-analysis. In: Otolaryngology - Head and Neck Surgery. 2008 ; Vol. 138, No. 3.
@article{dd174060386e488fa0595bb46ee42d90,
title = "Pediatric obstructive sleep apnea and quality of life: A meta-analysis",
abstract = "Objective: 1) To assess the quality of life (QOL) in children with obstructive sleep apnea (OSA) compared with QOL of children with chronic medical conditions, and 2) To determine QOL in children with OSA after adenotonsillectomy in short- and long-term follow-up. Data Sources/Review Methods: A literature review on QOL in pediatric OSA using the PubMed database. Results: The literature search yielded 10 articles that satisfied inclusion and exclusion criteria. In three studies, the Child Health Questionnaire (CHQ) survey was used to compare 193 patients who had OSA with 93 children who had juvenile rheumatoid arthritis (JRA) and with 815 healthy children. Of 12 CHQ subscale scores for children with OSA, 8 scores were significantly lower (indicating a poorer QOL) than controls. Children with OSA scored 19.23 points lower than healthy children in the subscale of parental impact-emotional. Children with OSA had QOL scores that were similar to those of children with JRA. In seven publications, 369 children with OSA undergoing adenotonsillectomy were studied by using the OSA-18 QOL instrument. The total OSA-18 score and each of the domain scores showed significant improvement (P < 0.0001) after adenotonsillectomy. At long-term follow-up, QOL scores remained significantly improved. Conclusions: Pediatric OSA has a significant impact on QOL. QOL in pediatric OSA is similar to that of children with JRA. Large improvements in QOL occur after adenotonsillectomy, and these findings are maintained in the long-term. The literature lacks control studies on QOL in pediatric OSA.",
author = "Baldassari, {Cristina M.} and Mitchell, {Ronald B.} and Christine Schubert and Rudnick, {Emily F.}",
year = "2008",
month = "3",
doi = "10.1016/j.otohns.2007.11.003",
language = "English (US)",
volume = "138",
journal = "Otolaryngology - Head and Neck Surgery (United States)",
issn = "0194-5998",
publisher = "Mosby Inc.",
number = "3",

}

TY - JOUR

T1 - Pediatric obstructive sleep apnea and quality of life

T2 - A meta-analysis

AU - Baldassari, Cristina M.

AU - Mitchell, Ronald B.

AU - Schubert, Christine

AU - Rudnick, Emily F.

PY - 2008/3

Y1 - 2008/3

N2 - Objective: 1) To assess the quality of life (QOL) in children with obstructive sleep apnea (OSA) compared with QOL of children with chronic medical conditions, and 2) To determine QOL in children with OSA after adenotonsillectomy in short- and long-term follow-up. Data Sources/Review Methods: A literature review on QOL in pediatric OSA using the PubMed database. Results: The literature search yielded 10 articles that satisfied inclusion and exclusion criteria. In three studies, the Child Health Questionnaire (CHQ) survey was used to compare 193 patients who had OSA with 93 children who had juvenile rheumatoid arthritis (JRA) and with 815 healthy children. Of 12 CHQ subscale scores for children with OSA, 8 scores were significantly lower (indicating a poorer QOL) than controls. Children with OSA scored 19.23 points lower than healthy children in the subscale of parental impact-emotional. Children with OSA had QOL scores that were similar to those of children with JRA. In seven publications, 369 children with OSA undergoing adenotonsillectomy were studied by using the OSA-18 QOL instrument. The total OSA-18 score and each of the domain scores showed significant improvement (P < 0.0001) after adenotonsillectomy. At long-term follow-up, QOL scores remained significantly improved. Conclusions: Pediatric OSA has a significant impact on QOL. QOL in pediatric OSA is similar to that of children with JRA. Large improvements in QOL occur after adenotonsillectomy, and these findings are maintained in the long-term. The literature lacks control studies on QOL in pediatric OSA.

AB - Objective: 1) To assess the quality of life (QOL) in children with obstructive sleep apnea (OSA) compared with QOL of children with chronic medical conditions, and 2) To determine QOL in children with OSA after adenotonsillectomy in short- and long-term follow-up. Data Sources/Review Methods: A literature review on QOL in pediatric OSA using the PubMed database. Results: The literature search yielded 10 articles that satisfied inclusion and exclusion criteria. In three studies, the Child Health Questionnaire (CHQ) survey was used to compare 193 patients who had OSA with 93 children who had juvenile rheumatoid arthritis (JRA) and with 815 healthy children. Of 12 CHQ subscale scores for children with OSA, 8 scores were significantly lower (indicating a poorer QOL) than controls. Children with OSA scored 19.23 points lower than healthy children in the subscale of parental impact-emotional. Children with OSA had QOL scores that were similar to those of children with JRA. In seven publications, 369 children with OSA undergoing adenotonsillectomy were studied by using the OSA-18 QOL instrument. The total OSA-18 score and each of the domain scores showed significant improvement (P < 0.0001) after adenotonsillectomy. At long-term follow-up, QOL scores remained significantly improved. Conclusions: Pediatric OSA has a significant impact on QOL. QOL in pediatric OSA is similar to that of children with JRA. Large improvements in QOL occur after adenotonsillectomy, and these findings are maintained in the long-term. The literature lacks control studies on QOL in pediatric OSA.

UR - http://www.scopus.com/inward/record.url?scp=39649108436&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=39649108436&partnerID=8YFLogxK

U2 - 10.1016/j.otohns.2007.11.003

DO - 10.1016/j.otohns.2007.11.003

M3 - Article

C2 - 18312869

AN - SCOPUS:39649108436

VL - 138

JO - Otolaryngology - Head and Neck Surgery (United States)

JF - Otolaryngology - Head and Neck Surgery (United States)

SN - 0194-5998

IS - 3

ER -