Pemphigus, pregnancy, and plasmapheresis

Sherry Shieh, Yisheng V. Fang, Joanne L. Becker, Allison Holm, Ernest H. Beutner, Thomas N. Helm

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Pemphigus vulgaris (PV) is an autoimmune blistering disorder that usually occurs in the fifth and sixth decades of life but may occur at younger ages and during pregnancy. Circulating intercellular antibodies directed at desmosomal proteins may cross the placenta and place children at risk for neonatal pemphigus (NP). We describe the case of a pregnant woman with PV treated successfully with a combination of systemic corticosteroids and plasmapheresis. The possibility of PV should be considered in any pregnant woman with a worsening, widespread, mucocutaneous, blistering disease. Plasmapheresis offers a useful alternative to immunosuppressive therapy in the setting of pregnancy.

Original languageEnglish (US)
Pages (from-to)327-329
Number of pages3
JournalCutis
Volume73
Issue number5
StatePublished - May 2004

Fingerprint

Pemphigus
Plasmapheresis
Pregnancy
Pregnant Women
Immunosuppressive Agents
Placenta
Adrenal Cortex Hormones
Antibodies
Proteins
Therapeutics

ASJC Scopus subject areas

  • Dermatology
  • Immunology and Allergy

Cite this

Shieh, S., Fang, Y. V., Becker, J. L., Holm, A., Beutner, E. H., & Helm, T. N. (2004). Pemphigus, pregnancy, and plasmapheresis. Cutis, 73(5), 327-329.

Pemphigus, pregnancy, and plasmapheresis. / Shieh, Sherry; Fang, Yisheng V.; Becker, Joanne L.; Holm, Allison; Beutner, Ernest H.; Helm, Thomas N.

In: Cutis, Vol. 73, No. 5, 05.2004, p. 327-329.

Research output: Contribution to journalArticle

Shieh, S, Fang, YV, Becker, JL, Holm, A, Beutner, EH & Helm, TN 2004, 'Pemphigus, pregnancy, and plasmapheresis', Cutis, vol. 73, no. 5, pp. 327-329.
Shieh S, Fang YV, Becker JL, Holm A, Beutner EH, Helm TN. Pemphigus, pregnancy, and plasmapheresis. Cutis. 2004 May;73(5):327-329.
Shieh, Sherry ; Fang, Yisheng V. ; Becker, Joanne L. ; Holm, Allison ; Beutner, Ernest H. ; Helm, Thomas N. / Pemphigus, pregnancy, and plasmapheresis. In: Cutis. 2004 ; Vol. 73, No. 5. pp. 327-329.
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