TY - JOUR
T1 - Penicillin Prophylaxis against Neonatal Streptococcal Infections
AU - Gotoff, Samuel P.
AU - Boyer, Kenneth M.
AU - Joffe, Alain
AU - Walker, Alexander M.
AU - Rothman, Kenneth J.
AU - Siegel, Jane D.
AU - Mccracken, George H.
AU - Rosenfeld, Charles R.
PY - 1981/2/19
Y1 - 1981/2/19
N2 - To the Editor: The report by Siegel et al. in the October 2 issue clearly shows that a single injection of penicillin given in the delivery room can decrease the incidence of postnatally acquired earlyonset Group B streptococcal infection. However, as the authors point out in their discussion of the one infant who had evidence of meningitis before penicillin was administered, penicillin will obviously not prevent infections that are already established at the time of birth. The issue is how many cases of early-onset Group B streptococcal disease are late intrauterine infections present at birth and thus not preventable by.
AB - To the Editor: The report by Siegel et al. in the October 2 issue clearly shows that a single injection of penicillin given in the delivery room can decrease the incidence of postnatally acquired earlyonset Group B streptococcal infection. However, as the authors point out in their discussion of the one infant who had evidence of meningitis before penicillin was administered, penicillin will obviously not prevent infections that are already established at the time of birth. The issue is how many cases of early-onset Group B streptococcal disease are late intrauterine infections present at birth and thus not preventable by.
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U2 - 10.1056/NEJM198102193040813
DO - 10.1056/NEJM198102193040813
M3 - Letter
C2 - 7005683
AN - SCOPUS:0019364609
VL - 304
SP - 484
EP - 485
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 8
ER -