Penile Cancer: Management of Regional Lymphatic Drainage

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Presence and magnitude of the inguinal nodal metastases are the most important determinants of oncologic outcome in patients with squamous carcinoma of the penis (SCP). Surgical removal of the inguinal lymph nodes provides an important staging and therapeutic benefit to SCP patients, while the methodology of appropriate patient selection for lymph node dissection continues to evolve. Compliant, motivated, and reliable patients with low risk of harboring metastatic inguinal lymph nodes can be managed with careful inguinal surveillance. In SCP patients whose primary tumors demonstrate pathologic features of aggressive disease, modified bilateral inguinal lymph node dissection should be performed and converted to classic ilioinguinal lymph node dissection if metastatic disease is confirmed on frozen sections. Patients with bulky inguinal metastases are unlikely to be cured by surgery alone. Integration of systemic therapy, especially in a presurgical setting, is an attractive strategy for management of patients with advanced SCP, and is currently being studied prospectively.

Original languageEnglish (US)
Pages (from-to)411-419
Number of pages9
JournalUrologic Clinics of North America
Volume37
Issue number3
DOIs
StatePublished - Aug 2010

Fingerprint

Penile Neoplasms
Groin
Drainage
Penis
Squamous Cell Carcinoma
Lymph Node Excision
Lymph Nodes
Neoplasm Metastasis
Frozen Sections
Patient Selection
Therapeutics

Keywords

  • Lymph nodes
  • Management
  • Penis
  • Squamous carcinoma
  • Urethra

ASJC Scopus subject areas

  • Urology

Cite this

Penile Cancer : Management of Regional Lymphatic Drainage. / Margulis, Vitaly; Sagalowsky, Arthur I.

In: Urologic Clinics of North America, Vol. 37, No. 3, 08.2010, p. 411-419.

Research output: Contribution to journalArticle

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