Percutaneous image-guided therapy of intra-abdominal malignancy: Imaging evaluation of treatment response

Ashraf Thabet, Sanjeeva Kalva, Debra A. Gervais

Research output: Contribution to journalArticle

27 Scopus citations

Abstract

The rising incidence of abdominal malignancies such as hepatocellular carcinoma (HCC) and renal cell carcinoma presents several challenges. Although surgery typically provides the best chance for cure, many patients are not surgical candidates. Innovative percutaneous therapies such as transarterial chemoembolization (TACE), radioembolization, and radiofrequency ablation (RFA) are increasingly being utilized as alternative treatment modalities, in some cases, with proven survival benefit. With the rise in interventional oncology, radiologists are being increasingly asked to interpret post-treatment imaging examinations that are critical to assessing treatment efficacy and complications. This article reviews the imaging manifestations of the most common percutaneous therapies, with special emphasis on TACE and RFA. Imaging findings of treatment-induced tumor necrosis, viable tumor, complications, and, in particular, benign ancillary findings that may be confused with viable tumor are reviewed, as manifested on computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET).

Original languageEnglish (US)
Pages (from-to)593-609
Number of pages17
JournalAbdominal Imaging
Volume34
Issue number5
DOIs
Publication statusPublished - Sep 2009

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Keywords

  • Ablation
  • Chemoembolization
  • Malignancy
  • Percutaneous
  • Radioembolization

ASJC Scopus subject areas

  • Gastroenterology
  • Urology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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