Percutaneous transluminal angioplasty: Association between depressive symptoms and diminished health status benefits

Kim G. Smolderen, David M. Safley, John A. House, John A. Spertus, Steven P. Marso

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Depressive symptoms are known to compromise health status in cardiac disease, but this relationship has not been described in peripheral artery disease (PAD). Depressive symptoms (PHQ-9) and disease-specific health status (Peripheral Artery Questionnaire, PAQ) were assessed in 242 PAD patients undergoing percutaneous transluminal angioplasty (PTA) at baseline and 1 year. Patients were classified by baseline and follow-up depression status (moderate-severe depressive symptoms = PHQ ≥ 10). Changes were categorized as no depression/improvement of depression versus persistent/worsened depression. At baseline, 20% of patients were depressed; at 1 year, 17% of patients experienced persistent/worsened depression. Although this group improved on most PAQ subscales, they improved to a significantly lesser degree than those without depressive symptoms or those who improved by 1 year (p-values < 0.05). Baseline depressive symptoms (B per 5-point increment = -11.9, 95% CI -15.3, -8.5, p < 0.0001) and changes in depression were independently associated with a decrease in 1-year health status (B per 5-point increment = -11.7, 95% CI -14.3, -9.2, p < 0.0001). In conclusion, depressive symptoms are associated with less improvement in health status 1 year after undergoing a peripheral endovascular revascularization (PER) as compared with those having no depression or whose depressive symptoms improve. Efforts to improve depression detection and treatment among patients with PAD may improve the health status outcomes of these patients.

Original languageEnglish (US)
Pages (from-to)260-266
Number of pages7
JournalVascular Medicine
Volume16
Issue number4
DOIs
StatePublished - Aug 2011

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Insurance Benefits
Angioplasty
Health Status
Depression
Peripheral Arterial Disease
Arteries
Heart Diseases

Keywords

  • angioplasty
  • depression
  • health status
  • peripheral vascular disease
  • revascularization

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Percutaneous transluminal angioplasty : Association between depressive symptoms and diminished health status benefits. / Smolderen, Kim G.; Safley, David M.; House, John A.; Spertus, John A.; Marso, Steven P.

In: Vascular Medicine, Vol. 16, No. 4, 08.2011, p. 260-266.

Research output: Contribution to journalArticle

Smolderen, Kim G. ; Safley, David M. ; House, John A. ; Spertus, John A. ; Marso, Steven P. / Percutaneous transluminal angioplasty : Association between depressive symptoms and diminished health status benefits. In: Vascular Medicine. 2011 ; Vol. 16, No. 4. pp. 260-266.
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