TY - JOUR
T1 - Perfluorocarbon liquids in ophthalmology
AU - Kramer, Steven G.
AU - Hwang, David
AU - Peyman, Gholam A.
AU - Schulman, Joel A.
AU - Sullivan, Brian
PY - 1995
Y1 - 1995
N2 - Perfluorocarbon liquids have been used to facilitate surgery in a wide variety of conditions, including proliferative vitreoretinopathy, giant retinal tears, drainge of suprachoroidal hemorrhages, diabetic traction, retinal detachments with a rhegmatogenous component, dislocated crystalline or intraocular lenses, and retinal detachment associated with choroidal coloboma. The clarity of perfluorocarbon liquids, with a refractive index close to that of water, allows the use of a conventional contact lens for vitreous surgery while the low viscosity facilitates tissue manipulation, injection, and removal. All perfluorocarbon liquids when used as tamponading agents can compress and disorganize the retina. This "toxicity" is a physical effect rather than chemical toxicity and depends upon the amount of perfluorocarbon liquid injected. Perfluorocarbon liquids are not tolerated in the anterior chamber, causing corneal edema within 2-3 days at the site of contact.
AB - Perfluorocarbon liquids have been used to facilitate surgery in a wide variety of conditions, including proliferative vitreoretinopathy, giant retinal tears, drainge of suprachoroidal hemorrhages, diabetic traction, retinal detachments with a rhegmatogenous component, dislocated crystalline or intraocular lenses, and retinal detachment associated with choroidal coloboma. The clarity of perfluorocarbon liquids, with a refractive index close to that of water, allows the use of a conventional contact lens for vitreous surgery while the low viscosity facilitates tissue manipulation, injection, and removal. All perfluorocarbon liquids when used as tamponading agents can compress and disorganize the retina. This "toxicity" is a physical effect rather than chemical toxicity and depends upon the amount of perfluorocarbon liquid injected. Perfluorocarbon liquids are not tolerated in the anterior chamber, causing corneal edema within 2-3 days at the site of contact.
KW - perfluorocarbon liquids
KW - retinal detachment
KW - vitreous substitutes
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U2 - 10.1016/S0039-6257(05)80093-1
DO - 10.1016/S0039-6257(05)80093-1
M3 - Article
C2 - 7604361
AN - SCOPUS:0028948090
SN - 0039-6257
VL - 39
SP - 375
EP - 395
JO - Survey of Ophthalmology
JF - Survey of Ophthalmology
IS - 5
ER -