Perfluoroctylbromide as a contrast agent for computed tomographic imaging of septic and aseptic arthritis

David J. Sartoris; Jose Guerra; Robert F. Mattrey; Donald Resnick; Parviz Haghighi; Roxanne Mitten; Debra Trudell; Deborah Pate

doi:10.1097/00004424-198601000-00009

Perfluoroctylbromide as a contrast agent for computed tomographic imaging of septic and aseptic arthritis

David J. Sartoris, Jose Guerra, Robert F. Mattrey, Donald Resnick, Parviz Haghighi, Roxanne Mitten, Debra Trudell, Deborah Pate

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Perfluoroctylbromide (PFOB), a perfluorocarbon macrophage-labeling contrast agent, was applied to computed tomographic imaging of septic and aseptic arthritis models in rabbits. Marked enhancement of induced pyarthrosis was observed in both the knee and the sacroiliac joint. Moderate enhancement was noted in tetracycline-induced synovitis of the knee. Sterile synovitis of the sacroiliac joint and simple knee joint effusion showed no enhance-ment. These results suggest that PFOB is a useful contrast medium for the diagnosis of and distinction between septic and sterile arthritis.

Original language	English (US)
Pages (from-to)	49-55
Number of pages	7
Journal	Investigative Radiology
Volume	21
Issue number	1
DOIs	https://doi.org/10.1097/00004424-198601000-00009
State	Published - Jan 1986

Keywords

Arthritis
Computed tomography
Computed tomography
Contrast enhancement
Contrast media
Pyogenic
Sacroiliac joint

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/00004424-198601000-00009

Cite this

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title = "Perfluoroctylbromide as a contrast agent for computed tomographic imaging of septic and aseptic arthritis",

abstract = "Perfluoroctylbromide (PFOB), a perfluorocarbon macrophage-labeling contrast agent, was applied to computed tomographic imaging of septic and aseptic arthritis models in rabbits. Marked enhancement of induced pyarthrosis was observed in both the knee and the sacroiliac joint. Moderate enhancement was noted in tetracycline-induced synovitis of the knee. Sterile synovitis of the sacroiliac joint and simple knee joint effusion showed no enhance-ment. These results suggest that PFOB is a useful contrast medium for the diagnosis of and distinction between septic and sterile arthritis.",

keywords = "Arthritis, Computed tomography, Computed tomography, Contrast enhancement, Contrast media, Pyogenic, Sacroiliac joint",

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AU - Sartoris, David J.

AU - Guerra, Jose

AU - Mattrey, Robert F.

AU - Resnick, Donald

AU - Haghighi, Parviz

AU - Mitten, Roxanne

AU - Trudell, Debra

AU - Pate, Deborah

PY - 1986/1

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N2 - Perfluoroctylbromide (PFOB), a perfluorocarbon macrophage-labeling contrast agent, was applied to computed tomographic imaging of septic and aseptic arthritis models in rabbits. Marked enhancement of induced pyarthrosis was observed in both the knee and the sacroiliac joint. Moderate enhancement was noted in tetracycline-induced synovitis of the knee. Sterile synovitis of the sacroiliac joint and simple knee joint effusion showed no enhance-ment. These results suggest that PFOB is a useful contrast medium for the diagnosis of and distinction between septic and sterile arthritis.

AB - Perfluoroctylbromide (PFOB), a perfluorocarbon macrophage-labeling contrast agent, was applied to computed tomographic imaging of septic and aseptic arthritis models in rabbits. Marked enhancement of induced pyarthrosis was observed in both the knee and the sacroiliac joint. Moderate enhancement was noted in tetracycline-induced synovitis of the knee. Sterile synovitis of the sacroiliac joint and simple knee joint effusion showed no enhance-ment. These results suggest that PFOB is a useful contrast medium for the diagnosis of and distinction between septic and sterile arthritis.

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Perfluoroctylbromide as a contrast agent for computed tomographic imaging of septic and aseptic arthritis

Abstract

Keywords

ASJC Scopus subject areas

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