Performance evaluation of hydroxylated and acylated silicone rubber coatings

Chi Chun Tsai, Michael L. Dollar, Anca Constantinescu, Padmakar V. Kulkarni, Robert C. Eberhart

Research output: Contribution to journalConference article

6 Scopus citations

Abstract

Hydroxylated and C16 acylated silicone rubber films were prepared with enhanced albumin binding. Lee-White clotting times were significantly increased for both treatments. Hydroxylation significantly reduced C5a production. Hydroxylated silicone rubber femoral vein catheters in canines reduced 111In-labeled platelet activity, compared with bilateral silicone rubber catheter controls. The results suggest hydroxylated silicone rubber films have enhanced biocompatibility.

Original languageEnglish (US)
Pages (from-to)M192-M193
JournalASAIO Transactions
Volume37
Issue number3
StatePublished - Jul 1991

ASJC Scopus subject areas

  • Biophysics

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